Relation of Body Mass Index to Symptom Burden in Patients withAtrial Fibrillation

Atrial fibrillation (AF) is the most common sustained arrhythmia and is associated with significant morbidity and increased mortality. As body mass index (BMI) is increasingly recognized as an important risk factor for the development of AF, we tested the hypothesis that BMI modulates symptomatic AF...

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Bibliographic Details
Published in:The American journal of cardiology 2018-07, Vol.122 (2), p.235-241
Main Authors: Chalazan, Brandon, Dickerman, Deanna, Sridhar, Arvind, Farrell, Maureen, Gayle, Katherine, Samuels, David C., Shoemaker, Benjamin, Darbar, Dawood
Format: Article
Language:English
Subjects:
Ablation
Anti-Arrhythmia Agents - therapeutic use
Arrhythmia
Atrial Fibrillation - epidemiology
Atrial Fibrillation - physiopathology
Atrial Fibrillation - therapy
Body mass
Body Mass Index
Body size
Cardiac arrhythmia
Catheter Ablation
Catheters
Comorbidity
Confidence intervals
Cross-Sectional Studies
Electrocardiography
Female
Fibrillation
Heart attacks
Heart failure
Humans
Male
Middle Aged
Morbidity
Obesity
Obesity - epidemiology
Patients
Quality of Life
Questionnaires
Recurrence
Registries
Retrospective Studies
Rhythm
Risk analysis
Risk Factors
Sleep apnea
United States - epidemiology
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Summary:Atrial fibrillation (AF) is the most common sustained arrhythmia and is associated with significant morbidity and increased mortality. As body mass index (BMI) is increasingly recognized as an important risk factor for the development of AF, we tested the hypothesis that BMI modulates symptomatic AF burden. Cross-sectional data collected from 1,382 patients in the Vanderbilt AF Registry were analyzed. AF severity was assessed using the Toronto atrial fibrillation severity scale (AFSS). BMI was categorized according to World Health Organization guidelines and patients were grouped according to their present AF treatment regimen: no treatment (n = 185), rate control therapy with atrioventricular nodal blocking agents (n = 351), rhythm control with antiarrhythmic drugs (n = 636), and previous AF ablation (n = 210). Patients with BMI >35 kg/m2 had higher AFSS scores than those with BMI
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2018.04.011