A Positive Correlation Between Gastric and Esophageal Dysmotility Suggests Common Causality

Background Gastric and esophageal dysmotility syndromes are some of the most common motility diagnoses, but little is known about their interrelationship. Aims The aim of our study was to determine if a correlation exists between gastric and esophageal dysmotility syndromes. Methods We reviewed the...

Full description

Saved in:
Bibliographic Details
Published in:Digestive diseases and sciences 2018-12, Vol.63 (12), p.3417-3424
Main Authors: Zikos, Thomas A., Clarke, John O., Triadafilopoulos, George, Regalia, Kirsten A., Sonu, Irene S., Fernandez-Becker, Nielsen Q., Nandwani, Monica C., Nguyen, Linda A.
Format: Article
Language:English
Subjects:
Biochemistry
Correlation of Data
Diabetes
Enteric Nervous System - physiopathology
Esophageal diseases
Esophageal Motility Disorders - diagnosis
Esophageal Motility Disorders - physiopathology
Esophagus
Esophagus - innervation
Esophagus - physiopathology
Female
Gastric Emptying - physiology
Gastroenterology
Gastrointestinal Transit - physiology
Gastroparesis - diagnosis
Gastroparesis - etiology
Gastroparesis - physiopathology
Hepatology
Humans
Male
Manometry - methods
Medicine
Medicine & Public Health
Middle Aged
Motility
Oncology
Original Article
Radionuclide Imaging - methods
Scleroderma (Disease)
Stomach - innervation
Stomach - physiopathology
Systemic scleroderma
Transplant Surgery
Transplantation of organs, tissues, etc
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Gastric and esophageal dysmotility syndromes are some of the most common motility diagnoses, but little is known about their interrelationship. Aims The aim of our study was to determine if a correlation exists between gastric and esophageal dysmotility syndromes. Methods We reviewed the records of all patients who underwent both solid gastric emptying scintigraphy (GES) and high-resolution esophageal manometry (HRM) within a 2 year period, with both done between August 2012 and August 2017. All GESs were classified as either rapid, normal, or delayed. All HRMs were classified according to the Chicago Classification 3.0. Correlations were assessed using Fisher’s exact test and multiple logistic regression. Results In total, 482 patients met inclusion criteria. Of patients with a normal, delayed, and rapid GES, 53.1, 64.5, and 77.3% had an abnormal HRM, respectively ( p  
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-018-5175-4