Comparison of serum lipid profile in type 2 diabetes with and without adequate diabetes control in Sudanese population in north of Sudan

Diabetes mellitus (DM) is a major health problem in Sudan and is a leading cause of morbidity and mortality. Dyslipidemia is a major complication of diabetes and an important risk factor for cardiovascular disease (CVD). The objective of this study was to determine the prevalence of dyslipidemia and...

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Published in:Diabetes & metabolic syndrome clinical research & reviews 2018-11, Vol.12 (6), p.961-964
Main Authors: Awadalla, Heitham, Noor, Sufian K., Elmadhoun, Wadie M., Bushara, Sarra O., Almobarak, Ahmed O., Sulaiman, Amel Abdalrhim, Ahmed, Mohamed H.
Format: Article
Language:English
Subjects:
Adult
Cross-Sectional Studies
Diabetes
Diabetes Mellitus, Type 2 - blood
Diabetes Mellitus, Type 2 - complications
Dyslipidemia
Dyslipidemias - complications
Dyslipidemias - epidemiology
Female
Glycated Hemoglobin A - metabolism
Humans
Lipids - blood
Male
Middle Aged
Prevalence
River Nile State
Sudan
Sudan - epidemiology
Young Adult
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Summary:Diabetes mellitus (DM) is a major health problem in Sudan and is a leading cause of morbidity and mortality. Dyslipidemia is a major complication of diabetes and an important risk factor for cardiovascular disease (CVD). The objective of this study was to determine the prevalence of dyslipidemia and its co-relation with the glycemic control in individuals with diabetes in River Nile State, Sudan. Individuals with diabetes attended, Naserudin Karamalla Diabetic (NKDM) Centre, in Atbara teaching hospital during study period, who volunteered to participate were included. Only those on treatment for DM for at least one year were included. Venous samples were collected for cholesterol, triglycerides, HDL, LDL, blood glucose and Glycosylated hemoglobin. Participants were interviewed using standardized pretested questionnaire to record medical history and sociodemographic characteristics. Blood pressure, body mass index (BMI) and waist circumference were measured. A total of 188 individuals were included. The mean age was 49.5 + 13.9 and (128) 68.1% were females. Most patients were having DM for at least 3–5 years 69 (36.7%). Poor diabetes control (HbA1c >7) was recorded in 87.2%, hypercholesterolemia, hypertriglyceridemia and high LDL were identified in 36.6%, 27.7% and 26.6% respectively. In addition, HDL was low in 61.2% of patients. Low HDL is a prominent feature in two thirds of individuals with diabetes, while high cholesterol and high triglyceride were seen in over one quarter.
ISSN:1871-4021
1878-0334
DOI:10.1016/j.dsx.2018.06.004