BRIEF EXPOSURES TO THETA-BURST MAGNETIC FIELDS IMPAIR THE CONSOLIDATION OF FOOD-INDUCED CONDITIONED PLACE PREFERENCE

Theta-burst magnetic fields (1 μT) designed to mimic electrical stimuli employed in vitro to affect long-term potentiation have been previously shown to impair the acquisition of conditioned fear. In the current study, the authors were interested in investigating whether similar magnetic fields coul...

Full description

Saved in:
Bibliographic Details
Published in:International journal of neuroscience 2007-02, Vol.117 (2), p.295-299
Main Authors: DELPARTE, J. J., PERSINGER, M. A.
Format: Article
Language:English
Subjects:
Animals
Behavior, Animal - radiation effects
conditioned place preference
Conditioning, Operant - physiology
Conditioning, Operant - radiation effects
Electromagnetic Fields - adverse effects
Electromagnetic Phenomena - methods
Food
Learning Disorders - etiology
Learning Disorders - physiopathology
long-term potentiation
magnetic fields
Male
Rats
Rats, Wistar
Time Factors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Theta-burst magnetic fields (1 μT) designed to mimic electrical stimuli employed in vitro to affect long-term potentiation have been previously shown to impair the acquisition of conditioned fear. In the current study, the authors were interested in investigating whether similar magnetic fields could affect the consolidation of food-induced conditioned place preference. Fourteen male Wistar rats were exposed to a theta-burst magnetic field (1 s pulse of 5 trains of an LTP-evoking pattern) continuously or with either a 5 s or 10 s interstimulus interval for 15 min immediately following 6 daily conditioning trials (15 min/day) in a place preference apparatus. Testing demonstrated the durations in the food-paired chamber was significantly shorter for all of the magnetic field-exposed groups compared to the sham-exposed group (they remained for longer periods in the food-paired chamber, typical of normal rats). In addition, the group exposed continuously to the LTP-magnetic field (1-ms interstimulus duration) displayed the least time in the food-paired chamber. The treatments explained 80% of the variance in durations within the experimental setting. These results suggest that exposures to theta-burst magnetic fields elicit amnesic effects for contextual stimuli.
ISSN:0020-7454
1563-5279
1543-5245
DOI:10.1080/00207450500535834