Amplification of hsa-miR-191/425 locus promotes breast cancer proliferation and metastasis by targeting DICER1

Abstract The dysregulation of micro RNAs (miRNAs) is a crucial characteristic of human cancers. Herein, we observed frequent amplification of the MIR191/425 locus in breast cancer, which is correlated with poor survival outcome. We demonstrated that the miR-191/425 cluster binds the 3′ untranslated...

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Bibliographic Details
Published in:Carcinogenesis (New York) 2018-12, Vol.39 (12), p.1506-1516
Main Authors: Zhang, Xiao, Wu, Mingming, Chong, Qing-Yun, Zhang, Weijie, Qian, Pengxu, Yan, Hong, Qian, Wenchang, Zhang, Min, Lobie, Peter E, Zhu, Tao
Format: Article
Language:English
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