Clinical manifestations and imaging findings of thrombosis of developmental venous anomalies

• Published in: Clinical radiology 2018-11, Vol.73 (11), p.985.e7-985.e12
• Main Authors: Assadsangabi, R., Mohan, S., Nabavizadeh, S.A.
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Central Nervous System Venous Angioma - complications; Central Nervous System Venous Angioma - diagnosis; Central Nervous System Venous Angioma - diagnostic imaging; Central Nervous System Venous Angioma - pathology; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuroimaging; Retrospective Studies; Tomography, X-Ray Computed; Venous Thrombosis - diagnostic imaging; Venous Thrombosis - etiology; Venous Thrombosis - pathology; Young Adult
• ISSN: 0009-9260; 1365-229X
• DOI: 10.1016/j.crad.2018.06.022

To determine clinical manifestations, imaging findings and outcome of patients with thrombosed developmental venous anomalies (DVAs). The radiology database was searched retrospectively for thrombosed DVAs between 01/01/2000 to 07/01/2016. Demographic variables, associated risk factors, clinical manifestations, imaging findings, treatments, and follow-up were recorded. Six patients were found (four female and two male; age range 16–45 years with mean age, 21.3 years). The most common clinical presentation was headaches followed by neurological deficits and seizures. Venous infarction, parenchymal haemorrhage, venous congestive oedema were noted as the radiological findings. Clinical outcome was favourable in all patients with complete recovery or persistence of mild neurological symptoms. Thrombosed DVAs may occur under rare circumstances, which lead to variable symptoms. Familiarity with this entity and early recognition of associated findings including venous infarction, parenchymal haemorrhage, and venous congestive oedema would help early diagnosis and prompt treatment. •DVA thrombosis may lead to venous ischaemic infarction, parenchymal haemorrhage, venous congestive oedema, or subarachnoid haemorrhage.•Developing linear signal/attenuation abnormality on MRI/CT scan is the most helpful sign in recognition of thrombosed DVA.•Early diagnosis could lead to the proper treatment.