Comparison of vestibular function between large cerebellopontine angle meningioma and schwannoma

Conclusion. Abnormal caloric and vestibular evoked myogenic potential (VEMP) responses are frequently encountered with a large cerebellopontine angle (CPA) schwannoma, while normal caloric responses and abnormal VEMPs are noted with a large CPA meningioma. This difference may possibly exist because...

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Bibliographic Details
Published in:Acta oto-laryngologica 2009-01, Vol.129 (2), p.161-165
Main Authors: Hu, Yi-Feng, Cheng, Po-Wen, Young, Yi-Ho
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Caloric test
Caloric Tests
Cerebellar Neoplasms - diagnosis
Cerebellar Neoplasms - physiopathology
Cerebellopontine Angle - physiopathology
cerebellopontine angle tumor
Electromyography
Electronystagmography
Evoked Potentials, Motor - physiology
Female
Humans
Magnetic Resonance Imaging
Male
Medical sciences
Meningeal Neoplasms - diagnosis
Meningeal Neoplasms - physiopathology
meningioma
Meningioma - diagnosis
Meningioma - physiopathology
Middle Aged
Neck Muscles - innervation
Neurology
Neuroma, Acoustic - diagnosis
Neuroma, Acoustic - physiopathology
Otorhinolaryngology. Stomatology
Reflex - physiology
schwannoma
Tumors of the nervous system. Phacomatoses
vestibular evoked myogenic potential
Vestibular Function Tests
Vestibular Nerve - physiopathology
Young Adult
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Summary:Conclusion. Abnormal caloric and vestibular evoked myogenic potential (VEMP) responses are frequently encountered with a large cerebellopontine angle (CPA) schwannoma, while normal caloric responses and abnormal VEMPs are noted with a large CPA meningioma. This difference may possibly exist because schwannoma causes vestibular deficits via parenchymal involvement, while vestibular deficits in the meningioma are mostly due to compression neuropathy. Objectives. This study aimed to compare the tumor characteristics in relation to vestibular function, i.e. caloric and VEMP responses, between large-sized (>2.5 cm) meningioma and schwannoma in the CPA. Patients and methods. Five patients with large CPA meningioma and nine patients with large CPA schwannoma were enrolled in this study. Each patient underwent a battery of tests including audiometry, caloric test, VEMP test, and MRI study. Results. The meningioma group showed 20% caloric abnormality and 75% VEMP abnormality, while the schwannoma group revealed 100% caloric and 100% VEMP abnormalities. A significant difference existed in relation to caloric abnormality between the two groups, but not in relation to VEMP abnormality.
ISSN:0001-6489
1651-2251
DOI:10.1080/00016480802126553