Sepsis incidence and mortality are underestimated in Australian intensive care unit administrative data

Objectives: To compare estimates of the incidence and mortality of sepsis and septic shock among patients in Australian intensive care units (ICUs) according to clinical diagnoses or binational intensive care database (ANZICS CORE) methodology. Design, setting, participants: Prospective inception co...

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Bibliographic Details
Published in:Medical journal of Australia 2018-09, Vol.209 (6), p.255-260
Main Authors: Heldens, Manon, Schout, Marinelle, Hammond, Naomi E, Bass, Frances, Delaney, Anthony, Finfer, Simon R
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Australia - epidemiology
Emergency medicine
Female
Hospital Mortality
Humans
Incidence
Infectious diseases
Intensive Care Units - statistics & numerical data
Male
Middle Aged
Prospective Studies
Sepsis - diagnosis
Sepsis - epidemiology
Sepsis - mortality
Statistics, Epidemiology and research design
Treatment Outcome
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Summary:Objectives: To compare estimates of the incidence and mortality of sepsis and septic shock among patients in Australian intensive care units (ICUs) according to clinical diagnoses or binational intensive care database (ANZICS CORE) methodology. Design, setting, participants: Prospective inception cohort study (3‐month inception period, 1 October – 31 December 2016, with 60‐day follow‐up); daily screening of all patients in a tertiary hospital 60‐bed multidisciplinary ICU. Main outcomes: Diagnoses of sepsis and septic shock according to clinical criteria and database criteria; in‐hospital mortality (censored at 60 days). Results: Of 864 patients admitted to the ICU, 146 (16.9%) were diagnosed with sepsis by clinical criteria and 98 (11%) according to the database definition (P
ISSN:0025-729X
1326-5377
DOI:10.5694/mja18.00168