Validation of simplified PESI score for identification of low-risk patients with pulmonary embolism: From the COMMAND VTE Registry

Background: The simplified pulmonary embolism severity index (sPESI) score has been reported to be useful in predicting 30-day mortality for patients with pulmonary embolism, which helps the identification of low-risk patients for early hospital discharge or home treatment. However, therapeutic deci...

Full description

Saved in:
Bibliographic Details
Published in:European heart journal. Acute cardiovascular care 2020-06, Vol.9 (4), p.262-270
Main Authors: Yamashita, Yugo, Morimoto, Takeshi, Amano, Hidewo, Takase, Toru, Hiramori, Seiichi, Kim, Kitae, Oi, Maki, Akao, Masaharu, Kobayashi, Yohei, Toyofuku, Mamoru, Izumi, Toshiaki, Tada, Tomohisa, Chen, Po-Min, Murata, Koichiro, Tsuyuki, Yoshiaki, Saga, Syunsuke, Sasa, Tomoki, Sakamoto, Jiro, Kinoshita, Minako, Togi, Kiyonori, Mabuchi, Hiroshi, Takabayashi, Kensuke, Shiomi, Hiroki, Kato, Takao, Makiyama, Takeru, Ono, Koh, Kimura, Takeshi
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Female
Follow-Up Studies
Humans
Incidence
Japan - epidemiology
Male
Pulmonary Embolism - diagnosis
Pulmonary Embolism - epidemiology
Pulmonary Embolism - etiology
Registries
Retrospective Studies
Risk Assessment - methods
Risk Factors
Severity of Illness Index
Survival Rate - trends
Venous Thromboembolism - complications
Venous Thromboembolism - diagnosis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: The simplified pulmonary embolism severity index (sPESI) score has been reported to be useful in predicting 30-day mortality for patients with pulmonary embolism, which helps the identification of low-risk patients for early hospital discharge or home treatment. However, therapeutic decision-making should also be based on the risks of adverse events other than mortality. Methods: The COMMAND VTE Registry is a multicentre registry enrolling consecutive patients with acute symptomatic venous thromboembolism in Japan between January 2010 and August 2014, and the current study population consisted of 1715 patients with pulmonary embolism. We calculated the sPESI score for each patient, and compared 30-day rates of mortality, recurrent venous thromboembolism and major bleeding between sPESI scores of 0 and 1 or greater. Results: Patients with a sPESI score of 0 accounted for 383 (22%) patients, and 110 (6.4%) patients died within 30 days. The cumulative 30-day incidence of mortality was lower in patients with a sPESI score of 0 than those with a sPESI score of 1 or greater (0.5% vs. 8.1%, log rank P
ISSN:2048-8726
2048-8734
DOI:10.1177/2048872618799993