Resection of Hepatic Lesions Perfused by the Cholecystic Vein Using Indocyanine Green Navigation in Patients with cT2 Gallbladder Cancer

Background Various approaches to hepatectomy have been proposed for cT2 gallbladder cancers (GBC), but the optimal management strategy remains unclear. The aim of this study is to assess the effectiveness of using an indocyanine green (ICG)-based intraoperative navigation system during hepatic resec...

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Bibliographic Details
Published in:World journal of surgery 2019-02, Vol.43 (2), p.608-614
Main Authors: Chiba, Naokazu, Shimazu, Motohide, Ochiai, Shigeto, Yokozuka, Kei, Gunji, Takahiro, Okihara, Masaaki, Sano, Toru, Tomita, Koichi, Tsutsui, Rina, Oshima, Go, Takano, Kiminori, Abe, Yuta, Hirano, Hiroshi, Kawachi, Shigeyuki
Format: Article
Language:English
Subjects:
Abdominal Surgery
Cancer
Cannulation
Cardiac Surgery
Fluorescence
Gallbladder
Gallbladder cancer
General Surgery
Hepatectomy
Lesions
Liver
Medical imaging
Medicine
Medicine & Public Health
Metastases
Metastasis
Navigation systems
Original Scientific Report (including Papers Presented at Surgical Conferences)
Patients
Surgery
Survival
Thoracic Surgery
Vascular Surgery
Weight
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Summary:Background Various approaches to hepatectomy have been proposed for cT2 gallbladder cancers (GBC), but the optimal management strategy remains unclear. The aim of this study is to assess the effectiveness of using an indocyanine green (ICG)-based intraoperative navigation system during hepatic resection for cT2 GBC. Methods From September 2007 to December 2017, 24 consecutive patients diagnosed with cT2 GBC underwent hepatic resection using ICG navigation. After cannulation of the cholecystic artery, ICG diluted with dissolution liquid was injected and ICG fluorescence illumination was visualized with the HyperEye Medical System. And additional histopathological examination was performed on the most recent 15 of the 24 patients for detection of microscopic liver metastasis. Results For all patients, the disease-free survival rate was 59.1% at 5 years and overall survival rate was 86.2% at 5 years. Microscopic liver metastasis was detected in the resected liver in 3 (20%) of 15 patients, whose site of liver was S6, S5, and S5, respectively. The weight of the liver resected using ICG navigation was significantly smaller than that of S4a/S5 segmentectomy ( P  
ISSN:0364-2313
1432-2323
DOI:10.1007/s00268-018-4810-8