Dendritic cells in sepsis: Potential immunoregulatory cells with therapeutic potential

[Display omitted] •Sepsis is a disease of immune dysregulation.•DCs are regulator of immune homeostasis and inflammatory process.•Sepsis-induces apoptotic death of DCs and tolerogenic DCs.•Sepsis reprograms immunometabolic status of DCs.•Targeting DCs may be a future novel immunomodulatory or immuno...

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Bibliographic Details
Published in:Molecular immunology 2018-09, Vol.101, p.615-626
Main Author: Kumar, V.
Format: Article
Language:English
Subjects:
cDCs
complement
cytokines
death
Dendritic cells
homeostasis
immune response
Immunometabolism
Immunosuppression
macrophages
monocytes
neutrophils
pathogenesis
pathogens
patients
pDCs
Sepsis
sepsis (infection)
T-lymphocytes
therapeutics
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