Central venous oxygen saturation is not predictive of early complications in cancer patients presenting to the emergency department

Central venous oxygen saturation (ScvO 2 ) is easily observable in oncology patients with long-term central venous catheters (CVC), and has been studied as a prognostic factor in patients with sepsis. We sought to investigate the association between ScvO 2 and early complications in cancer patients...

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Bibliographic Details
Published in:Internal and emergency medicine 2019-03, Vol.14 (2), p.281-289
Main Authors: Peyrony, Olivier, Dumas, Guillaume, Legay, Léa, Principe, Alessandra, Franchitti, Jessica, Simonetta, Marie, Verrat, Anne, Amami, Jihed, Milacic, Hélène, Bragança, Adélia, Gillet, Ariane, Resche-Rigon, Matthieu, Fontaine, Jean-Paul, Azoulay, Elie
Format: Article
Language:English
Subjects:
Aged
Area Under Curve
Blood pressure
Cancer
Catheterization, Central Venous - standards
Catheters
Central Venous Pressure - physiology
Complications
EM - Original
Emergency medical services
Emergency Service, Hospital - organization & administration
Emergency Service, Hospital - statistics & numerical data
Female
Health risks
Heart rate
Humans
Internal Medicine
Male
Medicine
Medicine & Public Health
Middle Aged
Multivariate analysis
Neoplasms - complications
Neoplasms - physiopathology
Neutropenia - etiology
Neutropenia - physiopathology
Oximetry - methods
Oximetry - standards
Oxygen
Oxygen - analysis
Oxygen - blood
Oxygen content
Oxygen saturation
Paris
Prospective Studies
ROC Curve
Saturation
Sepsis
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Summary:Central venous oxygen saturation (ScvO 2 ) is easily observable in oncology patients with long-term central venous catheters (CVC), and has been studied as a prognostic factor in patients with sepsis. We sought to investigate the association between ScvO 2 and early complications in cancer patients presenting to the ED. We prospectively enrolled adult cancer patients with pre-existing CVC who presented to the ED. ScvO 2 was measured on their CVC. The outcome was admission to the intensive care unit (ICU) or mortality by day 7. ScvO 2 was first studied as a continuous variable (%) with a ROC analysis and as a categorical variable (cut-off at  2 (OR 4.76; 95% CI 1.81–12.52 and OR 6.23, 95% CI 2.40–16.17, respectively). This study does not support the use of ScvO 2 to risk stratify cancer patients presenting to the ED.
ISSN:1828-0447
1970-9366
DOI:10.1007/s11739-018-1966-z