The development of a Core Outcome Set for medicines management interventions for people with dementia in primary care

Abstract Background people with dementia (PWD), and their carers, face challenges with medicines management activities. As interventions to support medicines management for PWD are developed, consideration must be given to the outcomes chosen to measure their effectiveness. A Core Outcome Set (COS)...

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Bibliographic Details
Published in:Age and ageing 2019-03, Vol.48 (2), p.260-266
Main Authors: McGrattan, Mairead, Barry, Heather E, Ryan, Cristín, Cooper, Janine A, Passmore, A Peter, Robinson, A Louise, Molloy, Gerard J, Darcy, Carmel M, Buchanan, Hilary, Hughes, Carmel M
Format: Article
Language:English
Subjects:
Academic staff
Aged
Caregivers
Clinical trials
Community pharmacists
Delphi method
Delphi Technique
Dementia
Dementia - drug therapy
Dementia - therapy
Dementia disorders
Disease management
Drugs
Experts
Family physicians
Female
Health care
Humans
Intervention
Interviews
Interviews as Topic
Male
Medical personnel
Medication Therapy Management - standards
Pharmacists
Primary care
Primary Health Care - methods
Primary Health Care - standards
Questionnaires
Stakeholder Participation
Systematic review
Systematic Reviews as Topic
Treatment Outcome
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Summary:Abstract Background people with dementia (PWD), and their carers, face challenges with medicines management activities. As interventions to support medicines management for PWD are developed, consideration must be given to the outcomes chosen to measure their effectiveness. A Core Outcome Set (COS) is a minimum set of outcomes to be measured in all trials in a particular clinical area, which seeks to reduce heterogeneity of outcome reporting across trials. Objective to develop a COS for trials assessing the effectiveness of medicines management interventions for PWD in primary care. Methods a comprehensive list of outcomes was compiled through a systematic review and semi-structured interviews with PWD (n = 18), their carers (n = 15), community pharmacists (n = 15) and general practitioners (n = 15). These outcomes were rated by a Delphi panel (n = 52) on a nine-point Likert scale from 1 (limited importance) to 9 (critical) during three sequential rounds of questionnaire distribution. The Delphi panel comprised participants with expertise in dementia and medicines management, including academics and healthcare professionals. An outcome was eligible for inclusion in the COS if ≥70% of participants rated it critical and
ISSN:0002-0729
1468-2834
DOI:10.1093/ageing/afy172