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Correlation Between Blood Transfusion and Blood Glucose Levels in Adult Living Donor Liver Transplantation

To evaluate the effect of dextrose contained in banked blood products on the changes of blood glucose levels in adult living donor liver transplantation patients retrospectively. Four hundred seventy-seven patients were divided into a non–blood transfusion (BT) group (G1) and a BT group (G2). The ch...

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Bibliographic Details
Published in:Transplantation proceedings 2018-11, Vol.50 (9), p.2645-2647
Main Authors: Huang, C.-J., Chang, C.-H., Cheng, K.-W., Chen, C.-L., Wu, S.-C., Shih, T.-H., Yang, S.-C., Lee, Y.-E., Huang, C.-E., Jawan, B., Wang, C.-H., Juang, S.-E.
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Language:English
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Summary:To evaluate the effect of dextrose contained in banked blood products on the changes of blood glucose levels in adult living donor liver transplantation patients retrospectively. Four hundred seventy-seven patients were divided into a non–blood transfusion (BT) group (G1) and a BT group (G2). The changes in blood glucose levels during the operation were compared using a Mann-Whitney U test, and a P value less than .05 was regarded as significant. No significant changes were detected in blood glucose levels after anesthesia, during dissection phase, in the anhepatic phase, or after reperfusion between the groups. Estimated blood loss for G1 (n = 89) and G2 (n = 388) were 718 ± 514 and 5804 ± 877 mL respectively, G1 had no blood transfusion but G2 had received 4350 ± 6230 mL leukocyte-poor red blood cell transfusion, the pre- and end operation hemoglobin for G1 and G2 were 13.2 ± 2.0, 10.2 ± 1.9 and 10.1 ± 1.6, 10.2 ± 1.9 mg/dL respectively, indicating that they were not under or over transfused. When banked blood products are used to replace ongoing blood loss, the dextrose contained in citrate-phosphate-dextrose-adenine seems to have no effect on the changes in the blood glucose levels of the recipients. •Blood transfusions of banked blood products are blamed as one of the causes of hyperglycemia because they are stored in anticoagulant citrate-phosphate-dextrose-adenine (CPDA-1) solution, which contains 432 mg/dL dextrose.•The results of our comparison of a no blood transfusion group and a blood transfusion group revealed that blood transfusions, even massive, did not affect the changes in serum glucose during similar living donor liver transplantation conditions.•When banked blood products are used to replace ongoing blood loss, the dextrose contained in CPDA-1 seems to have no effect on changes in the blood glucose levels of the recipients.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2018.02.203