Influence of mildly and moderately elevated pulmonary artery systolic pressure on post‐renal transplantation survival and graft function

Background Severe pulmonary hypertension (PH) has been associated with decreased post–kidney transplant survival and increased rate of long‐term cardiovascular complications. Despite a high prevalence of PH in patients with end‐stage renal disease, data on post‐transplant renal allograft survival in...

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Bibliographic Details
Published in:Echocardiography (Mount Kisco, N.Y.) N.Y.), 2019-01, Vol.36 (1), p.22-27
Main Authors: Wang, Stephani C., Garcia, Rachel, Torosoff, Mikhail, Fein, Steven A., Ashar, Ata, Chandolias, Nikolaos, Conti, David, Lyubarova, Radmila
Format: Article
Language:English
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Summary:Background Severe pulmonary hypertension (PH) has been associated with decreased post–kidney transplant survival and increased rate of long‐term cardiovascular complications. Despite a high prevalence of PH in patients with end‐stage renal disease, data on post‐transplant renal allograft survival in recipients with pre‐existing mild‐to‐moderate PH are limited. Methods The single‐center retrospective study cohort consisted of 192 consecutive (2008–2015) renal transplant recipients with documented pretransplantation transthoracic echocardiogram (TTE) pulmonary artery systolic pressure (PASP). Mean age was 50.9 ± 12.4 years, 36.5% were females, and 81.25% were Caucasians. Results Elevated PASP ≥ 37 mm Hg was present in 51 patients. Elevated PASP was more common in patients with decreased
ISSN:0742-2822
1540-8175
DOI:10.1111/echo.14192