Ankylosing Spinal Disease—Diagnosis and Treatment of Spine Fractures

• Published in: World neurosurgery 2019-03, Vol.123, p.e162-e170
• Main Authors: Vazan, Martin, Ryang, Yu-Mi, Barz, Melanie, Török, Elisabeth, Gempt, Jens, Meyer, Bernhard
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Ankylosing spondylitis; Comorbidity; Diffuse idiopathic skeletal hyperostosis; DISH; Female; Follow-Up Studies; Humans; Male; Middle Aged; Spinal Diseases - complications; Spinal Diseases - diagnosis; Spinal Diseases - mortality; Spinal Diseases - therapy; Spinal Fractures - diagnosis; Spinal Fractures - etiology; Spinal Fractures - mortality; Spinal Fractures - therapy; Spinal fusion; Spine - diagnostic imaging; Spine - surgery; Spine fracture; Treatment Outcome
• ISSN: 1878-8750; 1878-8769
• DOI: 10.1016/j.wneu.2018.11.108

In patients with ankylosing spinal disease, including ankylosing spondylitis and diffuse idiopathic skeletal hyperostosis, even low-impact trauma can lead to complex injuries. The injuries seem to be highly unstable and associated with greater mortality rates compared with the general spine trauma population. We reviewed the medical records of a consecutive series of 41 patients (34 men, 7 women) with ankylosing spinal disease and unstable traumatic spine injuries who were admitted to our department from 2007 to 2016. The mean patient age was 73.4 ± 12.7 years. Of the 41 patients, 24 (58.5%) had ankylosing spondylitis and 17 (41.5%) had diffuse idiopathic skeletal hyperostosis. Low-velocity accidents were documented in 38 patients (92.7%). The most frequent injuries were type B spine fractures (61.0%). Accompanying spinal epidural hematoma was detected using magnetic resonance imaging in 12 patients (29.3%) but was not found by radiography or computed tomography. Of the 41 patients, 24 (58.5%) presented with American Spinal Injury Association impairment scale (AIS) grade E, 6 (14.6%) with grade D, and 8 (19.6%) with grade C or worse. All the patients had undergone internal fixation. All but 1 (97.6%) had received posterior fixation. In 25 (61%), a combined approach was performed. Five patients died of early complications. Of the 36 discharged patients, 11 died during the follow-up period and 1 was lost to follow-up. The surviving 24 patients had a median follow-up of 733 ± 576 days; 21 had AIS grade E, 2 had AIS grade D, and 1 had AIS grade C. A thorough diagnostic evaluation with multislice computed tomography and magnetic resonance imaging can reveal injuries that would remain undetected on conventional radiographs. A combined approach or posterior-only fixation seems safe.