A cancer of undetermined significance: Incidental thyroid carcinoma

Introduction The incidence of thyroid cancer is increasing which can be attributed in part to improved ultrasonography (US) methods and increased detection of incidental thyroid carcinomas (ITC). We aimed to compare ITC with nonincidental thyroid carcinomas (NITC) in this study. Methods Retrospectiv...

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Bibliographic Details
Published in:Diagnostic cytopathology 2019-05, Vol.47 (5), p.412-416
Main Authors: Evranos, Berna, Polat, Sefika Burcak, Cuhaci, Fatma Neslihan, Baser, Husniye, Topaloglu, Oya, Kilicarslan, Aydan, Kilic, Mehmet, Ersoy, Reyhan, Cakir, Bekir
Format: Article
Language:English
Subjects:
Biopsy
Cytology
Histology
Histopathology
incidental thyroid cancer
Iodide peroxidase
Lesions
Lymph nodes
Metastases
non‐incidental thyroid cancer
Peroxidase
Thyroglobulin
Thyroid cancer
Thyroid carcinoma
Thyroid diseases
Thyroid-stimulating hormone
Thyroidectomy
Thyroiditis
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Summary:Introduction The incidence of thyroid cancer is increasing which can be attributed in part to improved ultrasonography (US) methods and increased detection of incidental thyroid carcinomas (ITC). We aimed to compare ITC with nonincidental thyroid carcinomas (NITC) in this study. Methods Retrospective analyses of 906 individual patients who were operated for benign and malignant thyroid disease and had a final histopathological diagnosis of thyroid carcinoma were enrolled in this study. Preoperative US examination and fine needle aspiration (FNA) biopsy results were evaluated. The tumor foci in thyroidectomy specimens that were not represented in preoperative US or FNA reports were classified as ITC. The tumor foci that match with the lesions defined in US or FNA results were classified as NITC. Results Final histology revealed ITC in 326 patients (36%) and NITC in 580 patients (64% Mean age was 51.7 ± 11.11 in ITC group and 48.15 ± 13.1 in NITC group (P 
ISSN:8755-1039
1097-0339
DOI:10.1002/dc.24117