Scale-based diffusive image filtering preserving boundary sharpness and fine structures

• Published in: IEEE transactions on medical imaging 2001-11, Vol.20 (11), p.1140-1155
• Main Authors: Saha, P.K., Udupa, J.K.
• Format: Article
• Language: English
• Subjects: Adaptive filters; Algorithms; Anisotropic magnetoresistance; Biological and medical sciences; Brain - anatomy & histology; Brain - blood supply; Brain - diagnostic imaging; Fourier Analysis; Humans; Image analysis; Image processing; Image Processing, Computer-Assisted - instrumentation; Image Processing, Computer-Assisted - standards; Imaging phantoms; Information filtering; Information filters; Investigative techniques, diagnostic techniques (general aspects); Magnetic resonance; Magnetic resonance imaging; Magnetic Resonance Imaging - instrumentation; Magnetic Resonance Imaging - standards; Magnetic separation; Medical sciences; Methods; Miscellaneous. Technology; Models, Structural; Models, Theoretical; Multiple Sclerosis - diagnosis; Multiple Sclerosis - diagnostic imaging; NMR; Noise; Nuclear magnetic resonance; Phantoms, Imaging - standards; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Radiography; Signal to noise ratio; Smoothing methods; Weights and Measures - standards
• ISSN: 0278-0062; 1558-254X
• DOI: 10.1109/42.963817

Image acquisition techniques often suffer from low signal-to-noise ratio (SNR) and/or contrast-to-noise ratio (CNR). Although many acquisition techniques are available to minimize these, post acquisition filtering is a major off-line image processing technique commonly used to improve the SNR and CNR. A major drawback of filtering is that it often diffuses/blurs important structures along with noise. Here, the authors introduce two scale-based filtering methods that use local structure size or "object scale" information to arrest smoothing around fine structures and across even low-gradient boundaries. The first of these methods uses a weighted average over a scale-dependent neighborhood while the other employs scale-dependent diffusion conductance to perform filtering. Both methods adaptively modify the degree of filtering at any image location depending on local object scale. Object scale allows the authors to accurately use a restricted homogeneity parameter for filtering in regions with fine details and in the vicinity of boundaries while a generous parameter in the interiors of homogeneous regions. Qualitative experiments based on both phantoms and patient magnetic resonance images show significant improvements using the scale-based methods over the extant anisotropic diffusive filtering method in preserving fine details and sharpness of object boundaries. Quantitative analyses utilizing 25 phantom images generated under a range of conditions of blurring, noise, and background variation confirm the superiority of the new scale-based approaches.