Outcomes after aortic valve replacement for aortic valve stenosis, with or without concomitant coronary artery bypass grafting

• Published in: General thoracic and cardiovascular surgery 2019-06, Vol.67 (6), p.510-517
• Main Authors: Sakakura, Reo, Asai, Tohru, Suzuki, Tomoaki, Kinoshita, Takeshi, Enomoto, Masahide, Kondo, Yasuo, Shiraishi, Shoichiro
• Format: Article
• Language: English
• Subjects: Aortic stenosis; Cardiac arrhythmia; Cardiac Surgery; Cardiology; Cardiovascular disease; Coronary vessels; Diabetes; Heart attacks; Heart failure; Heart surgery; Hemodialysis; Hyperlipidemia; Medicine; Medicine & Public Health; Mortality; Original Article; Patients; Prostheses; Regression analysis; Surgical Oncology; Thoracic Surgery; Vein & artery diseases
• ISSN: 1863-6705; 1863-6713
• DOI: 10.1007/s11748-018-1053-4

Objectives To assess the effects of concomitant coronary artery bypass grafting (CABG), we analyzed the outcomes after aortic valve replacement (AVR) for aortic stenosis (AS) with and without coronary artery bypass grafting (CABG) at our institution. Methods Between 2002 and 2014, 605 consecutive patients underwent AVR for AS. Of these, the 275 who received isolated AVR (Group A) and the 122 who received both AVR and CABG (Group AC) patients were enrolled, after the exclusion of 8 patients who underwent reoperation and 200 who received other concomitant surgery. AVR and all bypass anastomoses were performed under intermittent retrograde cold blood cardioplegia. Multivariate analysis was used to assess any association of concomitant CABG with morbidity and mortality. Kaplan–Meier analysis was used to assess all-cause mortality. Results No significant difference in 30-day mortality was found between Group A and Group AC (1.5% vs. 0.8%, P  = 1.000). Nor did post-discharge survival differ significantly between the two groups ( P  = 0.20). Likewise, multivariate analysis showed that concomitant CABG was not associated with significantly greater in-hospital or mid-term mortality. Operative morbidities were comparable between the two groups, in terms of stroke (1.8% vs. 3.3%, P  = 0.466), prolonged ventilation (4.0% vs. 5.5%, P  = 0.565), deep sternal infection (1.8% vs. 3.3%, P  = 0.466), and acute renal failure (0.4% vs. 1.6% P  = 0.176). Conclusions Concomitant CABG at the time of AVR was performed without increasing early- or mid-term mortality. This absence of increased risk deserves consideration when choosing between different treatment strategies.