Inspiratory muscle strength training improves lung function in patients with the hypermobile Ehlers–Danlos syndrome: A randomized controlled trial

As exertional inspiratory dyspnea is a common disabling complaint in hypermobile Ehlers–Danlos syndrome (hEDS) often also known as joint hypermobility syndrome (JHS), we investigated inspiratory muscle (IM) strength in patients with hEDS, and we assessed the effects of IM training (IMT) on IM streng...

Full description

Saved in:
Bibliographic Details
Published in:American journal of medical genetics. Part A 2019-03, Vol.179 (3), p.356-364
Main Authors: Reychler, Gregory, Liistro, Giuseppe, Piérard, Gérald E., Hermanns‐Lê, Trinh, Manicourt, Daniel
Format: Article
Language:English
Subjects:
Adult
Anxiety
Clinical trials
connective tissue disease associated lung disease
Dyspnea
Ehlers-Danlos syndrome
Ehlers-Danlos Syndrome - diagnosis
Ehlers-Danlos Syndrome - physiopathology
Ehlers-Danlos Syndrome - therapy
Exercise
Female
Humans
Lung - physiopathology
lung physiology
Lungs
Male
Mental depression
Middle Aged
Muscle Strength
Physical Conditioning, Human - methods
Pressure
Resistance Training - methods
Respiration
Respiratory function
Respiratory Function Tests
Spirometry
Treatment Outcome
Walking
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:As exertional inspiratory dyspnea is a common disabling complaint in hypermobile Ehlers–Danlos syndrome (hEDS) often also known as joint hypermobility syndrome (JHS), we investigated inspiratory muscle (IM) strength in patients with hEDS, and we assessed the effects of IM training (IMT) on IM strength, lung function, and exercise capacity. A prospective evaluation of IM strength followed by a randomized controlled trial of IMT was performed in women with hEDS. Sniff nasal inspiratory pressure (SNIP) was used to routinely measure IM strength and IMT was carried out using a pressure threshold device. IM strength (main outcome), cardiopulmonary function, exercise capacity, and emotional distress of both the treated and control groups were evaluated at the start and at the end of the 6‐week training period. IM strength was reduced (
ISSN:1552-4825
1552-4833
DOI:10.1002/ajmg.a.61016