Predominance of blaCTX-M-65 and blaCTX-M-55 in extended-spectrum β-lactamase-producing Escherichia coli from raw retail chicken in South Korea

•First characterisation of extended-spectrum β-lactamase-producing E. coli (ESBL-EC) from raw retail chicken in South Korea.•blaCTX-M-65 was the predominant ESBL gene in ESBL-EC isolates from chicken.•Multidrug resistance is highly common in ESBL-EC from retail chicken in South Korea.•ESBL-EC isolat...

Full description

Saved in:
Bibliographic Details
Published in:Journal of global antimicrobial resistance. 2019-06, Vol.17, p.216-220
Main Authors: Park, Hyeeun, Kim, Jinshil, Ryu, Sangryeol, Jeon, Byeonghwa
Format: Article
Language:English
Subjects:
Antimicrobial resistance
Chicken
CTX-M
ESBL
Escherichia coli
Extended-spectrum β-lactamase
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•First characterisation of extended-spectrum β-lactamase-producing E. coli (ESBL-EC) from raw retail chicken in South Korea.•blaCTX-M-65 was the predominant ESBL gene in ESBL-EC isolates from chicken.•Multidrug resistance is highly common in ESBL-EC from retail chicken in South Korea.•ESBL-EC isolates from retail chicken in South Korea possess virulence genes of extraintestinal pathogenic E. coli (ExPEC). Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) are a serious public health concern worldwide. The aim of this study was to characterise ESBL-EC isolated from raw retail chicken in South Korea. The antimicrobial resistance, phylogenetic group and virulence gene prevalence of 67 ESBL-EC isolated from retail chicken in South Korea were investigated. All of the isolates possessed blaCTX-M genes, predominantly blaCTX-M-65 (52.2%) and blaCTX-M-55 (25.4%), and three isolates harboured both blaCTX-M-65 and blaCTX-M-55. More than one-half of the ESBL-EC strains also carried blaTEM. Antimicrobial susceptibility testing revealed that 98.5% of the strains were multidrug-resistant (MDR). Phylogenetic analysis showed that group A was predominant (56.7%), followed by B1 (19.4%), E (8.9%), B2 (6.0%) and D (6.0%). Virulence genes associated with extraintestinal pathogenic E. coli (ExPEC) were frequently detected in isolates of phylogenetic groups B1, B2, D and E. The results in this study demonstrate that retail chicken in South Korea is highly contaminated with MDR ESBL-EC and may serve as a reservoir for transmitting ExPEC to humans.
ISSN:2213-7165
2213-7173
DOI:10.1016/j.jgar.2019.01.005