Stress hyperglycemia: A prospective study examining the relationship between glucose, cortisol and diabetes in myocardial infarction

We aimed to explore the relationship between stress, hyperglycemia and diabetes in myocardial infarction (MI), using serum cortisol as a surrogate marker for the severity of stress. Subjects with acute MI were prospectively recruited upon hospital admission. Serum glucose and cortisol were measured...

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Bibliographic Details
Published in:Journal of diabetes and its complications 2019-04, Vol.33 (4), p.329-334
Main Authors: Cheung, N. Wah, Wong, K.Y. Carmen, Kovoor, Pramesh, McLean, Mark
Format: Article
Language:English
Subjects:
Chromium
Cortisol
Diabetes
Diabetes mellitus
Enzymes
Fasting
Gender
Glucose
Heart attacks
Hormones
Hyperglycemia
Immunoassay
Metabolism
Myocardial infarction
Stress hyperglycemia
Variables
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Summary:We aimed to explore the relationship between stress, hyperglycemia and diabetes in myocardial infarction (MI), using serum cortisol as a surrogate marker for the severity of stress. Subjects with acute MI were prospectively recruited upon hospital admission. Serum glucose and cortisol were measured in addition to standard testing. Subjects were defined as having stress hyperglycemia (SH) if they had an admission glucose ≥7.8 mmol/L without a history of glucose intolerance. Subjects were followed up with glucose tolerance testing post-discharge. Of the 200 subjects in the study, 58 had known diabetes/impaired glucose tolerance (IGT), and 45 had SH. There was a positive association between admission glucose and cortisol for the entire cohort (rs = 0.26, p 
ISSN:1056-8727
1873-460X
DOI:10.1016/j.jdiacomp.2018.12.015