Stenosis and revascularization of the coronary artery are associated with outcomes in presumed cardiogenic arrest survivors: A multi-center retrospective cohort study

• Published in: Resuscitation 2019-04, Vol.137, p.52-60
• Main Authors: Tsai, Min-Shan, Sung, Chih-Wei, Chen, Wen-Jone, Chuang, Po-Ya, Wang, Chih-Hung, Wu, Yen-Wen, Chang, Wei-Tien, Chen, Wei-Ting, Huang, Chien-Hua
• Format: Article
• Language: English
• Subjects: Aged; Cardiac arrest; Cardiopulmonary Resuscitation; Coronary Angiography; Coronary artery stenosis; Coronary Stenosis - diagnostic imaging; Coronary Stenosis - mortality; Coronary Stenosis - surgery; Female; Heart Arrest - diagnostic imaging; Heart Arrest - mortality; Heart Arrest - surgery; Hospital Mortality; Humans; Male; Middle Aged; Myocardial Revascularization - adverse effects; Neurological outcome; Percutaneous coronary intervention; Retrospective Studies; Survival; Survival Rate; Survivors; Taiwan
• ISSN: 0300-9572; 1873-1570
• DOI: 10.1016/j.resuscitation.2019.01.040

The emergent coronary angiography (CAG) is associated with better outcomes in CA survivors. However, the impact of severity and revascularization of coronary artery stenosis on outcomes in cardiac arrest (CA) survivors remains unclear. A total of 273 non-traumatic adult CA survivors who underwent emergent CAG from January 2011 to July 2017 were retrospectively recruited. The stenosis and non-revascularization of an individual coronary artery ≥70% were defined as significant in any of the major coronary arteries based on an operator visual estimate. There were 201 patients (73.63%) had ≧1 significant coronary artery stenosis and 58 patients (21.25%) with ≧1 non-revascularized coronary artery. The increased number of stenosed coronary artery was associated with an increased risk for in-hospital mortality [1-vessel: adjusted hazard ration (HR) 2.27, 95% confidence interval (CI) = 1.43–4.04, p = 0.021; 2-vessel: adjusted HR 5.49, 95% CI=2.17–13.89, p