Prevalence of drug use among adults with intellectual disabilities compared with drug use in the general population

• Published in: Pharmacoepidemiology and drug safety 2019-03, Vol.28 (3), p.337-344
• Main Authors: Hove, Oddbjørn, Biringer, Eva, Havik, Odd E., Assmus, Jörg, Braatveit, Kirsten J., Holm, Silje Elisabeth Hasmo, Hermann, Monica
• Format: Article
• Language: English
• Subjects: Adult; Age; Age Factors; Aged; Cardiovascular diseases; Cardiovascular Diseases - drug therapy; Case-Control Studies; Drug delivery; Drug use; Female; Health problems; Humans; Intellectual disabilities; Intellectual Disability; Life span; Logistic Models; Male; Middle Aged; Nervous system; Norway; Pharmacoepidemiology; Polypharmacy; Prevalence; psycholeptics; Young Adult
• ISSN: 1053-8569; 1099-1557
• DOI: 10.1002/pds.4741

Purpose Individuals with intellectual disabilities (IDs) have more health problems, a poorer general health, and a shorter life expectancy than individuals in general. High rates of drug use in IDs have been reported. Despite the increasing interest in health problems in individuals with IDs, little is known about their drug use. Method Drug use in a community sample of adults with IDs (N = 593) was compared with dispensed drugs in a time‐, age‐, and region‐matched comparison group of adults in Western Norway (N = 289 325). A logistic regression model was employed by using the main group effect to describe and analyze the differences between the ID sample and the comparison sample and by using the interaction term (group × age) to describe the rate change differences from the reference age (18‐30 years) between the two groups. Results Total drug use in the ID sample was 62% compared with 50% in the reference sample (P = 0.0001). The high prevalence of drugs for the nervous system (ATC N) in the ID sample (50%) explained the difference. From age 51 and over, the increase in the drug use rate for the cardiovascular disease was significantly lower in the ID sample than in the reference sample (P value range: 0.002‐0.019). Conclusions Adults with IDs use more drugs than adults in general. However, the findings showed lower rates of drug use in the ID sample than in the general population for drugs targeting diseases that are the leading causes of death in individuals with IDs.