Laparoscopic excision of deeply infiltrating endometriosis: a prospective observational study assessing perioperative complications in 244 patients

• Published in: Archives of gynecology and obstetrics 2019-06, Vol.299 (6), p.1619-1626
• Main Authors: Khazali, Shaheen, Gorgin, Atefeh, Mohazzab, Arash, Kargar, Roxana, Padmehr, Roya, Shadjoo, Khadije, Minas, Vasilis
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Bladder; Demographics; Endocrinology; Endometriosis; Endometriosis - surgery; Female; General Gynecology; Gynecological surgery; Gynecology; Human Genetics; Humans; Infertility; Laparoscopy; Laparoscopy - methods; Ligaments; Medical referrals; Medicine; Medicine & Public Health; Middle Aged; Observational studies; Obstetrics; Obstetrics/Perinatology/Midwifery; Pain; Patients; Postoperative Complications - etiology; Prospective Studies; Rectal Diseases - surgery; Standard deviation; Studies; Surgeons; Surgery; Surgical outcomes; Treatment Outcome; Urology; Womens health; Young Adult
• ISSN: 0932-0067; 1432-0711
• DOI: 10.1007/s00404-019-05144-6

Purpose To examine peri-operative complications in patients undergoing laparoscopic excision of deeply infiltrating endometriosis (DIE). Methods This was a prospective study of a case series of women having laparoscopic excision of deeply infiltrating endometriosis from September 2013 through August 2016 in a tertiary referral center for endometriosis and minimally invasive gynaecological surgery in Iran. Data collected included demographics, baseline characteristics, intraoperative and postoperative data up to 1 month following surgery. Results We analysed data from 244 consecutive patients, who underwent radical laparoscopic excision of all visible DIE. Major postoperative complications occurred in 3 (1.2%) and minor complications in 27 (11.1%) of patients. 80.3% of our patient group had Stage IV endometriosis. Segmental bowel resection was performed in 34 (13.9%), disc resection in 7 (2.9%), rectal shave in 53 (21.7%). Joint operating between a gynaecologist and colorectal and/or urological colleague was required in 29.6% of cases. The mean operating time was 223.8 min (± 80.7 standard deviation, range 60–440 min) and mean hospital stay was 2.9 days (± 1.5 standard deviation, range 1–11). The conversion to laparotomy rate was 1.6%. Conclusions A combination of different laparoscopic surgical techniques to completely excise all visible DIE, within the context of a tertiary referral center offering multi-disciplinary approach, produces safe outcomes with low complication rates.