The Bayley-III scale may underestimate neurodevelopmental disability after cardiac surgery in infants

• Published in: European journal of cardio-thoracic surgery 2020-01, Vol.57 (1), p.63-71
• Main Authors: Goldstone, Andrew B, Baiocchi, Michael, Wypij, David, Stopp, Christian, Andropoulos, Dean B, Atallah, Joseph, Atz, Andrew M, Beca, John, Donofrio, Mary T, Duncan, Kim, Ghanayem, Nancy S, Goldberg, Caren S, Hövels-Gürich, Hedwig, Ichida, Fukiko, Jacobs, Jeffrey P, Justo, Robert, Latal, Beatrice, Li, Jennifer S, Mahle, William T, McQuillen, Patrick S, Menon, Shaji C, Pike, Nancy A, Pizarro, Christian, Shekerdemian, Lara S, Synnes, Anne, Williams, Ismée A, Bellinger, David C, Newburger, Jane, Gaynor, J William
• Format: Article
• Language: English
• ISSN: 1010-7940; 1873-734X
• DOI: 10.1093/ejcts/ezz123

Abstract OBJECTIVES Neurodevelopmental disability is the most common complication among congenital heart surgery survivors. The Bayley scales are standardized instruments to assess neurodevelopment. The most recent edition (Bayley Scales of Infant and Toddler Development 3rd Edition, Bayley-III) yields better-than-expected scores in typically developing and high-risk infants than the second edition (Bayley Scales of Infant Development 2nd Edition, BSID-II). We compared BSID-II and Bayley-III scores in infants undergoing cardiac surgery. METHODS We evaluated 2198 infants who underwent operations with cardiopulmonary bypass between 1996 and 2009 at 26 institutions. We used propensity score matching to limit confounding by indication in a subset of patients (n = 705). RESULTS Overall, unadjusted Bayley-III motor scores were higher than BSID-II Psychomotor Development Index scores (90.7 ± 17.2 vs 77.6 ± 18.8, P