Distribution of cell types differs in Papanicolaou tests of squamous cell carcinomas and adenocarcinomas

Introduction Successful cervical cancer screening has led to decreasing numbers of malignant Papanicolaou tests in most laboratories. A previous study demonstrated a greater trend to unsatisfactory Papanicolaou tests in women with squamous carcinoma when compared with adenocarcinoma cases. However,...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American Society of Cytopathology JASC 2017-01, Vol.6 (1), p.10-15
Main Authors: Conrad, Rachel, MD, Wentzensen, Nicolas, MD, PhD, Zhang, Roy R., MD, Wang, Sophia, PhD, Schiffman, Mark, MD, MPH, Gold, Michael, MD, Walker, Joan, MD, Zuna, Rosemary E., MD
Format: Article
Language:English
Subjects:
Cancer screening
Cervical neoplasms
Cytodiagnosis
Liquid-based cytology
Pathology
Unsatisfactory
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Introduction Successful cervical cancer screening has led to decreasing numbers of malignant Papanicolaou tests in most laboratories. A previous study demonstrated a greater trend to unsatisfactory Papanicolaou tests in women with squamous carcinoma when compared with adenocarcinoma cases. However, adenocarcinomas were less frequently recognized as malignant. Materials and methods In an effort to elucidate differences in Papanicolaou tests from these tumor types, the relative distribution of cells was blindly and semi-quantitatively assessed in ThinPrep Papanicolaou slides from 332 women with biopsy-proven squamous carcinoma (237 cases), adenocarcinoma (45), and noninvasive lesions (50). Results Significant differences ( P 0.004) were more prominent in squamous carcinomas. The number of endocervical cells ( P  
ISSN:2213-2945
2213-2945
DOI:10.1016/j.jasc.2016.08.003