Engineering NADH/NAD+ ratio in Halomonas bluephagenesis for enhanced production of polyhydroxyalkanoates (PHA)

Halomonas bluephagenesis has been developed as a platform strain for the next generation industrial biotechnology (NGIB) with advantages of resistances to microbial contamination and high cell density growth (HCD), especially for production of polyhydroxyalkanoates (PHA) including poly(3-hydroxybuty...

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Bibliographic Details
Published in:Metabolic engineering 2018-09, Vol.49, p.275-286
Main Authors: Ling, Chen, Qiao, Guan-Qing, Shuai, Bo-Wen, Olavarria, Karel, Yin, Jin, Xiang, Rui-Juan, Song, Kun-Nan, Shen, Yun-Hao, Guo, Yingying, Chen, Guo-Qiang
Format: Article
Language:English
Subjects:
acetic acid
biotechnology
carbon
composite polymers
cost effectiveness
electron transfer
energy
engineering
etf
flavoproteins
glucose
Halomonas
metabolism
microbial contamination
NAD (coenzyme)
NADH
NADH/NAD
NADP (coenzyme)
Next generation industrial biotechnology
operon
oxygen
Oxygen limitation
PHB
Polyhydroxyalkanoates
pyruvic acid
redox potential
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