Diastereoselective α‑Amination of N-tert-Butanesulfinyl Imidates Using N‑Aryl‑N‑diphenylphosphinyldiazenes

Diastereoselective α-amination of N-tert-butanesulfinyl imidates has been developed using N-aryl (or N-tert-butyl) N-diphenylphosphinyldiazenes as nitrogen sources. The chiral 1-azaenolates derived from imidates undergo nucleophilic addition with diazenes to give α-hydrazino imidates in good yields....

Full description

Saved in:
Bibliographic Details
Published in:Journal of organic chemistry 2019-06, Vol.84 (11), p.7207-7218
Main Authors: Li, Zheng-Fei, Yao, Yun, Xu, Yan-Jun, Lu, Chong-Dao
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Diastereoselective α-amination of N-tert-butanesulfinyl imidates has been developed using N-aryl (or N-tert-butyl) N-diphenylphosphinyldiazenes as nitrogen sources. The chiral 1-azaenolates derived from imidates undergo nucleophilic addition with diazenes to give α-hydrazino imidates in good yields.
ISSN:0022-3263
1520-6904
DOI:10.1021/acs.joc.9b00877