Interval Walking Improves Glycemic Control and Body Composition After Cancer Treatment: A Randomized Controlled Trial

Abstract Context Patients with colorectal cancer have increased risk of metabolic diseases including diabetes. Exercise training may counteract metabolic dysregulation, but the impact of exercise training on glycemic control, including postprandial glycemia, has never been explored in patients with...

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Published in:The journal of clinical endocrinology and metabolism 2019-09, Vol.104 (9), p.3701-3712
Main Authors: Christensen, Jesper F, Sundberg, Anna, Osterkamp, Jens, Thorsen-Streit, Sarah, Nielsen, Anette B, Olsen, Cecilie K, Djurhuus, Sissal S, Simonsen, Casper, Schauer, Tim, Ellingsgaard, Helga, Østerlind, Kell, Krarup, Peter-Martin, Mosgaard, Camilla, Vistisen, Kirsten, Tolver, Anders, Pedersen, Bente K, Hojman, Pernille
Format: Article
Language:English
Subjects:
Biomarkers - analysis
Blood glucose
Blood Glucose - analysis
Body composition
Body fat
Cancer
Cancer therapies
Case-Control Studies
Clinical trials
Colorectal cancer
Colorectal carcinoma
Diabetes mellitus
Dual energy X-ray absorptiometry
Exercise
Female
Fitness training programs
Follow-Up Studies
Glucose
Glucose tolerance
Glucose Tolerance Test
Humans
Hyperglycemia - prevention & control
Hypoglycemia - prevention & control
Male
Metabolic disorders
Middle Aged
Neoplasms - rehabilitation
Neoplasms - therapy
Oxygen Consumption
Patients
Physical training
Prognosis
Prospective Studies
Quality of Life
Walking
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Summary:Abstract Context Patients with colorectal cancer have increased risk of metabolic diseases including diabetes. Exercise training may counteract metabolic dysregulation, but the impact of exercise training on glycemic control, including postprandial glycemia, has never been explored in patients with colorectal cancer. Objective To examine the effects of home-based interval walking on aerobic and metabolic fitness and quality of life in patients with colorectal cancer. Design Randomized controlled trial. Setting Clinical research center. Participants Thirty-nine sedentary (
ISSN:0021-972X
1945-7197
DOI:10.1210/jc.2019-00590