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The effect of nuchal cord on perinatal mortality and long-term offspring morbidity
Objective To evaluate perinatal and long-term cardiovascular and respiratory morbidities of children born with nuchal cord. Study design A large population-based cohort analysis of singleton deliveries was conducted. Maternal and birth characteristics, as well as cardiovascular and respiratory morbi...
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| Published in: | Journal of perinatology 2020-03, Vol.40 (3), p.439-444 |
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| Language: | English |
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| cites | cdi_FETCH-LOGICAL-c498t-ae415ce74d2d39527b1a581a33ae0673ffa48d7e0eea546a2ac425e4c21c2f323 |
| container_end_page | 444 |
| container_issue | 3 |
| container_start_page | 439 |
| container_title | Journal of perinatology |
| container_volume | 40 |
| creator | Masad, Roee Gutvirtz, Gil Wainstock, Tamar Sheiner, Eyal |
| description | Objective
To evaluate perinatal and long-term cardiovascular and respiratory morbidities of children born with nuchal cord.
Study design
A large population-based cohort analysis of singleton deliveries was conducted. Maternal and birth characteristics, as well as cardiovascular and respiratory morbidity incidence were evaluated. Kaplan–Meier survival curves were used to compare cumulative hospitalization incidence between groups. Cox regression models were used to control for possible confounders and follow-up length.
Results
243,682 deliveries were included. Of them, 34,332 (14.1%) were diagnosed with nuchal cord. Perinatal mortality rate was comparable between groups (0.5 vs. 0.6%,
p
= 0.16). Kaplan–Meier survival curves demonstrated no significant differences in cumulative cardiovascular or respiratory morbidity incidence between groups (log rank
p
= 0.69 and
p
= 0.10, respectively). Cox regression models reaffirmed a comparable risk for hospitalization between groups (aHR = 0.99 (95% CI 0.85–1.14,
p
= 0.87) and aHR = 0.97 (95% CI 0.92–1.02,
p
= 0.28).
Conclusions
Nuchal cord is not associated with higher rate of perinatal mortality nor long-term cardiorespiratory morbidity. |
| doi_str_mv | 10.1038/s41372-019-0511-x |
| format | article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2303201434</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A618258131</galeid><sourcerecordid>A618258131</sourcerecordid><originalsourceid>FETCH-LOGICAL-c498t-ae415ce74d2d39527b1a581a33ae0673ffa48d7e0eea546a2ac425e4c21c2f323</originalsourceid><addsrcrecordid>eNp9kl1rFTEQhoMo9lj9Ad7IgiDepCaZZDfnshS_oCBIvQ452ck5W3aTY5KF9t-bZWu1opKLgcnzTmYmLyEvOTvjDPS7LDl0gjK-pUxxTm8ekQ2XXUuVkvCYbFgngWqQ7Ql5lvM1Y8tl95ScAFdbxYTYkK9XB2zQe3Slib4JszvYsXEx9U0MzRHTEGypmSmmGoZy29jQN2MMe1owTVXj87FC-4XYDX0lnpMn3o4ZX9zFU_Ltw_uri0_08svHzxfnl9TJrS7UouTKYSd70cNWiW7HrdLcAlhkbQfeW6n7DhmiVbK1wjopFEonuBMeBJySt2vdY4rfZ8zFTEN2OI42YJyzEcBA1JFBVvT1H-h1nFOo3RmxrEQqruG_FLS1R63rwu-pvR3RDMHHkqxbnjbnLdeizgALdfYXqp4ep8HFgH6o-QeCN78JDmjHcshxnMsQQ34I8hV0Keac0Ju6_8mmW8OZWWxhVluYaguz2MLcVM2ru8nm3YT9veKnDyogVmD9TEy_Rv931R8YJ78m</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2363958841</pqid></control><display><type>article</type><title>The effect of nuchal cord on perinatal mortality and long-term offspring morbidity</title><source>LexisNexis - News & Business</source><source>Springer Nature</source><creator>Masad, Roee ; Gutvirtz, Gil ; Wainstock, Tamar ; Sheiner, Eyal</creator><creatorcontrib>Masad, Roee ; Gutvirtz, Gil ; Wainstock, Tamar ; Sheiner, Eyal</creatorcontrib><description>Objective
To evaluate perinatal and long-term cardiovascular and respiratory morbidities of children born with nuchal cord.
Study design
A large population-based cohort analysis of singleton deliveries was conducted. Maternal and birth characteristics, as well as cardiovascular and respiratory morbidity incidence were evaluated. Kaplan–Meier survival curves were used to compare cumulative hospitalization incidence between groups. Cox regression models were used to control for possible confounders and follow-up length.
Results
243,682 deliveries were included. Of them, 34,332 (14.1%) were diagnosed with nuchal cord. Perinatal mortality rate was comparable between groups (0.5 vs. 0.6%,
p
= 0.16). Kaplan–Meier survival curves demonstrated no significant differences in cumulative cardiovascular or respiratory morbidity incidence between groups (log rank
p
= 0.69 and
p
= 0.10, respectively). Cox regression models reaffirmed a comparable risk for hospitalization between groups (aHR = 0.99 (95% CI 0.85–1.14,
p
= 0.87) and aHR = 0.97 (95% CI 0.92–1.02,
p
= 0.28).
Conclusions
Nuchal cord is not associated with higher rate of perinatal mortality nor long-term cardiorespiratory morbidity.</description><identifier>ISSN: 0743-8346</identifier><identifier>EISSN: 1476-5543</identifier><identifier>DOI: 10.1038/s41372-019-0511-x</identifier><identifier>PMID: 31595022</identifier><language>eng</language><publisher>New York: Nature Publishing Group US</publisher><subject>692/499 ; 692/700/1750/1747 ; Adult ; Asphyxia neonatorum ; Cardiovascular Diseases - etiology ; Causes of ; Cesarean section ; Child development ; Female ; Follow-Up Studies ; Health aspects ; Humans ; Infant, Newborn ; Kaplan-Meier Estimate ; Maternal Age ; Meconium aspiration syndrome ; Medicine ; Medicine & Public Health ; Morbidity ; Mortality ; Nuchal Cord - complications ; Nuchal Cord - mortality ; Offspring ; Pediatric research ; Pediatric Surgery ; Pediatrics ; Perinatal Mortality ; Population studies ; Pregnancy ; Pregnancy Outcome ; Proportional Hazards Models ; Regression analysis ; Regression models ; Respiratory Tract Diseases - etiology ; Retrospective Studies ; Risk factors ; Survival ; Umbilical cord</subject><ispartof>Journal of perinatology, 2020-03, Vol.40 (3), p.439-444</ispartof><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2019</rights><rights>COPYRIGHT 2020 Nature Publishing Group</rights><rights>2019© The Author(s), under exclusive licence to Springer Nature America, Inc. 2019</rights><rights>The Author(s), under exclusive licence to Springer Nature America, Inc. 2019.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c498t-ae415ce74d2d39527b1a581a33ae0673ffa48d7e0eea546a2ac425e4c21c2f323</citedby><cites>FETCH-LOGICAL-c498t-ae415ce74d2d39527b1a581a33ae0673ffa48d7e0eea546a2ac425e4c21c2f323</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31595022$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Masad, Roee</creatorcontrib><creatorcontrib>Gutvirtz, Gil</creatorcontrib><creatorcontrib>Wainstock, Tamar</creatorcontrib><creatorcontrib>Sheiner, Eyal</creatorcontrib><title>The effect of nuchal cord on perinatal mortality and long-term offspring morbidity</title><title>Journal of perinatology</title><addtitle>J Perinatol</addtitle><addtitle>J Perinatol</addtitle><description>Objective
To evaluate perinatal and long-term cardiovascular and respiratory morbidities of children born with nuchal cord.
Study design
A large population-based cohort analysis of singleton deliveries was conducted. Maternal and birth characteristics, as well as cardiovascular and respiratory morbidity incidence were evaluated. Kaplan–Meier survival curves were used to compare cumulative hospitalization incidence between groups. Cox regression models were used to control for possible confounders and follow-up length.
Results
243,682 deliveries were included. Of them, 34,332 (14.1%) were diagnosed with nuchal cord. Perinatal mortality rate was comparable between groups (0.5 vs. 0.6%,
p
= 0.16). Kaplan–Meier survival curves demonstrated no significant differences in cumulative cardiovascular or respiratory morbidity incidence between groups (log rank
p
= 0.69 and
p
= 0.10, respectively). Cox regression models reaffirmed a comparable risk for hospitalization between groups (aHR = 0.99 (95% CI 0.85–1.14,
p
= 0.87) and aHR = 0.97 (95% CI 0.92–1.02,
p
= 0.28).
Conclusions
Nuchal cord is not associated with higher rate of perinatal mortality nor long-term cardiorespiratory morbidity.</description><subject>692/499</subject><subject>692/700/1750/1747</subject><subject>Adult</subject><subject>Asphyxia neonatorum</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Causes of</subject><subject>Cesarean section</subject><subject>Child development</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Kaplan-Meier Estimate</subject><subject>Maternal Age</subject><subject>Meconium aspiration syndrome</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Morbidity</subject><subject>Mortality</subject><subject>Nuchal Cord - complications</subject><subject>Nuchal Cord - mortality</subject><subject>Offspring</subject><subject>Pediatric research</subject><subject>Pediatric Surgery</subject><subject>Pediatrics</subject><subject>Perinatal Mortality</subject><subject>Population studies</subject><subject>Pregnancy</subject><subject>Pregnancy Outcome</subject><subject>Proportional Hazards Models</subject><subject>Regression analysis</subject><subject>Regression models</subject><subject>Respiratory Tract Diseases - etiology</subject><subject>Retrospective Studies</subject><subject>Risk factors</subject><subject>Survival</subject><subject>Umbilical cord</subject><issn>0743-8346</issn><issn>1476-5543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kl1rFTEQhoMo9lj9Ad7IgiDepCaZZDfnshS_oCBIvQ452ck5W3aTY5KF9t-bZWu1opKLgcnzTmYmLyEvOTvjDPS7LDl0gjK-pUxxTm8ekQ2XXUuVkvCYbFgngWqQ7Ql5lvM1Y8tl95ScAFdbxYTYkK9XB2zQe3Slib4JszvYsXEx9U0MzRHTEGypmSmmGoZy29jQN2MMe1owTVXj87FC-4XYDX0lnpMn3o4ZX9zFU_Ltw_uri0_08svHzxfnl9TJrS7UouTKYSd70cNWiW7HrdLcAlhkbQfeW6n7DhmiVbK1wjopFEonuBMeBJySt2vdY4rfZ8zFTEN2OI42YJyzEcBA1JFBVvT1H-h1nFOo3RmxrEQqruG_FLS1R63rwu-pvR3RDMHHkqxbnjbnLdeizgALdfYXqp4ep8HFgH6o-QeCN78JDmjHcshxnMsQQ34I8hV0Keac0Ju6_8mmW8OZWWxhVluYaguz2MLcVM2ru8nm3YT9veKnDyogVmD9TEy_Rv931R8YJ78m</recordid><startdate>20200301</startdate><enddate>20200301</enddate><creator>Masad, Roee</creator><creator>Gutvirtz, Gil</creator><creator>Wainstock, Tamar</creator><creator>Sheiner, Eyal</creator><general>Nature Publishing Group US</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QG</scope><scope>7QL</scope><scope>7RV</scope><scope>7T5</scope><scope>7T7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20200301</creationdate><title>The effect of nuchal cord on perinatal mortality and long-term offspring morbidity</title><author>Masad, Roee ; Gutvirtz, Gil ; Wainstock, Tamar ; Sheiner, Eyal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c498t-ae415ce74d2d39527b1a581a33ae0673ffa48d7e0eea546a2ac425e4c21c2f323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>692/499</topic><topic>692/700/1750/1747</topic><topic>Adult</topic><topic>Asphyxia neonatorum</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Causes of</topic><topic>Cesarean section</topic><topic>Child development</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Health aspects</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Kaplan-Meier Estimate</topic><topic>Maternal Age</topic><topic>Meconium aspiration syndrome</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Morbidity</topic><topic>Mortality</topic><topic>Nuchal Cord - complications</topic><topic>Nuchal Cord - mortality</topic><topic>Offspring</topic><topic>Pediatric research</topic><topic>Pediatric Surgery</topic><topic>Pediatrics</topic><topic>Perinatal Mortality</topic><topic>Population studies</topic><topic>Pregnancy</topic><topic>Pregnancy Outcome</topic><topic>Proportional Hazards Models</topic><topic>Regression analysis</topic><topic>Regression models</topic><topic>Respiratory Tract Diseases - etiology</topic><topic>Retrospective Studies</topic><topic>Risk factors</topic><topic>Survival</topic><topic>Umbilical cord</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Masad, Roee</creatorcontrib><creatorcontrib>Gutvirtz, Gil</creatorcontrib><creatorcontrib>Wainstock, Tamar</creatorcontrib><creatorcontrib>Sheiner, Eyal</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database (ProQuest)</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database (Proquest)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest Biological Science Journals</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of perinatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Masad, Roee</au><au>Gutvirtz, Gil</au><au>Wainstock, Tamar</au><au>Sheiner, Eyal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of nuchal cord on perinatal mortality and long-term offspring morbidity</atitle><jtitle>Journal of perinatology</jtitle><stitle>J Perinatol</stitle><addtitle>J Perinatol</addtitle><date>2020-03-01</date><risdate>2020</risdate><volume>40</volume><issue>3</issue><spage>439</spage><epage>444</epage><pages>439-444</pages><issn>0743-8346</issn><eissn>1476-5543</eissn><abstract>Objective
To evaluate perinatal and long-term cardiovascular and respiratory morbidities of children born with nuchal cord.
Study design
A large population-based cohort analysis of singleton deliveries was conducted. Maternal and birth characteristics, as well as cardiovascular and respiratory morbidity incidence were evaluated. Kaplan–Meier survival curves were used to compare cumulative hospitalization incidence between groups. Cox regression models were used to control for possible confounders and follow-up length.
Results
243,682 deliveries were included. Of them, 34,332 (14.1%) were diagnosed with nuchal cord. Perinatal mortality rate was comparable between groups (0.5 vs. 0.6%,
p
= 0.16). Kaplan–Meier survival curves demonstrated no significant differences in cumulative cardiovascular or respiratory morbidity incidence between groups (log rank
p
= 0.69 and
p
= 0.10, respectively). Cox regression models reaffirmed a comparable risk for hospitalization between groups (aHR = 0.99 (95% CI 0.85–1.14,
p
= 0.87) and aHR = 0.97 (95% CI 0.92–1.02,
p
= 0.28).
Conclusions
Nuchal cord is not associated with higher rate of perinatal mortality nor long-term cardiorespiratory morbidity.</abstract><cop>New York</cop><pub>Nature Publishing Group US</pub><pmid>31595022</pmid><doi>10.1038/s41372-019-0511-x</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0743-8346 |
| ispartof | Journal of perinatology, 2020-03, Vol.40 (3), p.439-444 |
| issn | 0743-8346 1476-5543 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2303201434 |
| source | LexisNexis - News & Business; Springer Nature |
| subjects | 692/499 692/700/1750/1747 Adult Asphyxia neonatorum Cardiovascular Diseases - etiology Causes of Cesarean section Child development Female Follow-Up Studies Health aspects Humans Infant, Newborn Kaplan-Meier Estimate Maternal Age Meconium aspiration syndrome Medicine Medicine & Public Health Morbidity Mortality Nuchal Cord - complications Nuchal Cord - mortality Offspring Pediatric research Pediatric Surgery Pediatrics Perinatal Mortality Population studies Pregnancy Pregnancy Outcome Proportional Hazards Models Regression analysis Regression models Respiratory Tract Diseases - etiology Retrospective Studies Risk factors Survival Umbilical cord |
| title | The effect of nuchal cord on perinatal mortality and long-term offspring morbidity |
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