Synthesis and application of magnetic-surfaced pseudo molecularly imprinted polymers for zearalenone pretreatment in cereal samples

• Published in: Food chemistry 2020-03, Vol.308, p.125696-125696, Article 125696
• Main Authors: Huang, Zhipeng, He, Juan, Li, Huayu, Zhang, Ming, Wang, Huige, Zhang, Yunxia, Li, Yuanyuan, You, Liqin, Zhang, Shusheng
• Format: Article
• Language: English
• Subjects: Adsorption; Avena - chemistry; Cereal sample; Chromatography, High Pressure Liquid; Edible Grain - chemistry; Magnetic surface molecularly imprinted polymers; Magnetics; Molecular Imprinting - methods; Polymers - chemistry; Pretreatment method; Solid Phase Extraction - methods; Triticum - chemistry; Warfarin pseudo template; Zea mays - chemistry; Zearalenone; Zearalenone - chemistry; μ-SPE
• ISSN: 0308-8146; 1873-7072
• DOI: 10.1016/j.foodchem.2019.125696

•Magnetic hollysite nanotubes were prepared and modified with vinyl.•Magnetic surface molecularly imprinted polymers were synthesized.•Synthetic polymers combined with μ-SPE as the pretreatment method for zearalenone.•The pretreatment method was developed and evaluated. Zearalenone (ZEA) is a fungal contaminant widely found in grains. In cereal samples, trace zearalenone was extracted and enriched using magnetic-surfaced pseudo molecularly imprinted polymers (SPMIPs) and detected. SPMIPs were prepared with Fe3O4 as the magnetic core, modified halloysites nanotubes as supporting materials, and selective imprinted polymers as shells. Vinyl was modified on the surface of halloysites nanotube. SPMIPs were synthesized with pseudo templates. SPMIPs as the adsorbent of dispersed-solid phase extraction (μ-SPE) were used to purify and enrich ZEA from maize samples. After optimized, the pretreatment method was evaluated. The linearity of the method was ranged within 10–200 ng mL−1. LOD and LOQ were 2.5 ng mL−1 and 8 ng mL−1 respectively. The ZEA spiking recoveries in maize samples ranged within 74.95–88.41% were with good RSDs lower than 4.25%. The developed method was successful applied in maize, oat, and wheat sample treatments and compared.