Effectiveness of mindfulness‐based cognitive therapy in patients with anxiety disorders in secondary‐care settings: A randomized controlled trial

• Published in: Psychiatry and clinical neurosciences 2020-02, Vol.74 (2), p.132-139
• Main Authors: Ninomiya, Akira, Sado, Mitsuhiro, Park, Sunre, Fujisawa, Daisuke, Kosugi, Teppei, Nakagawa, Atsuo, Shirahase, Joichiro, Mimura, Masaru
• Format: Article
• Language: English
• Subjects: Adult; Aged; Agoraphobia - therapy; Anxiety disorders; Cognitive ability; Cognitive Behavioral Therapy; Cognitive therapy; Confidence intervals; Drug therapy; Female; Humans; Male; Middle Aged; Mindfulness; Mindfulness - methods; Outcome Assessment, Health Care; Panic Disorder - therapy; Phobia, Social - therapy; randomized controlled trial; Secondary Care; Young Adult
• ISSN: 1323-1316; 1440-1819; 1440-1819
• DOI: 10.1111/pcn.12960

Aim The primary objective of this study was to examine the effectiveness of mindfulness‐based cognitive therapy (MBCT) in secondary‐care settings where the vast majority of the patients have already undergone pharmacotherapy but have not remitted. Methods Eligible participants were aged between 20 and 75 years and met the criteria for panic disorder/agoraphobia or social anxiety disorder specified in the DSM‐IV. They were randomly assigned to either the MBCT group (n = 20) or the wait‐list control group (n = 20). The primary outcome was the difference in mean change scores between pre‐ and post‐intervention assessments on the State–Trait Anxiety Inventory (STAI). The outcome was analyzed using an intent‐to‐treat approach and a mixed‐effect model repeated measurement. Results We observed significant differences in mean change scores for the STAI State Anxiety subscale (difference, −10.1; 95% confidence interval, −16.9 to −3.2; P