The perspectives of ethanol usage as an internal standard for the quantification of volatile compounds in alcoholic products by GC‐MS

The potential use of ethanol as an internal standard (IS) for GC‐MS analysis was studied. The paper describes the analysis of spirit drinks and other alcoholic products which consist of a mixture of water, ethanol, and volatile compounds. In the suggested method, ethanol was employed as an IS for th...

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Bibliographic Details
Published in:Journal of mass spectrometry. 2020-03, Vol.55 (3), p.e4493-n/a
Main Authors: Korban, Anton, Charapitsa, Siarhei, Čabala, Radomír, Lidia, Sobolenko, Sytova, Svetlana
Format: Article
Language:English
Subjects:
Alcoholic beverages
alcoholic products
Analysis
Dilution
Ethanol
GC‐MS
internal standard
Isotopes
Linearity
Photomultiplier tubes
Products
quantification
Saturation
Volatile compounds
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Summary:The potential use of ethanol as an internal standard (IS) for GC‐MS analysis was studied. The paper describes the analysis of spirit drinks and other alcoholic products which consist of a mixture of water, ethanol, and volatile compounds. In the suggested method, ethanol was employed as an IS for the common procedure of volatile compounds quantification. A number of standard solutions of nine compounds with different concentrations was prepared in a water‐ethanol matrix and measured with GC‐MS in the SIM mode. Two possible approaches were suggested to avoid detector saturation during ethanol detection. The first one consisted in using less abundant m/z 47 as quantifiers. These ions mainly correspond to unfragmented heavy ethanol molecules containing one 13C isotope. The second method consisted in reduction of the voltage of MS electron multiplier. The experiment also included the preparation and subsequent dilution of the standard solution and ethanol with water, which determined the linearity of the modified MS response relative to the ethanol content. Analysis of the obtained results revealed that volatile compounds can be successfully accurately determined with GC‐MS by employing ethanol as an IS. Application of the suggested method is not limited to the reported volatile compounds and alcoholic products.
ISSN:1076-5174
1096-9888
DOI:10.1002/jms.4493