Pressure–impedance analysis: Assist the diagnosis and classification of ineffective esophageal motility disorder

Background and Aim We elucidated the clinical significance of distal contractile integral‐to‐esophageal impedance integral (EII) ratio (DCIIR) in ineffective esophageal motility (IEM) adult patients. Methods We recruited 101 patients with IEM (48.38 ± 1.58 years) and 42 matched healthy volunteers (4...

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Published in:Journal of gastroenterology and hepatology 2020-08, Vol.35 (8), p.1317-1324
Main Authors: Wu, Jia‐Feng, Tsai, I‐Jung, Tong, Tzu‐Wei, Lin, Yi‐Cheng, Yang, Chia‐Hsiang, Tseng, Ping‐Huei
Format: Article
Language:English
Subjects:
bolus transit
Classification
Contractility
Diagnosis
distal contractile to impedance integral ratio
esophageal manometry
Esophagus
ineffective esophageal motility
Motility
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Summary:Background and Aim We elucidated the clinical significance of distal contractile integral‐to‐esophageal impedance integral (EII) ratio (DCIIR) in ineffective esophageal motility (IEM) adult patients. Methods We recruited 101 patients with IEM (48.38 ± 1.58 years) and 42 matched healthy volunteers (44.28 ± 1.85 years) in this case–control study. All subjects underwent esophageal high‐resolution impedance manometry from October 2014 to May 2018. The diagnosis of IEM was based on the Chicago Classification version 3.0. The EII, EII ratio, and DCIIR were analyzed by matlab software. Results The EII, EII ratio, and DCIIR calculated at an impedance threshold of 1500 Ω (EII1500, EII ratio1500, and DCIIR1500, respectively) were significantly lower in the IEM group than in healthy controls (P 
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.14981