New Nocobactin Derivatives with Antimuscarinic Activity, Terpenibactins A–C, Revealed by Genome Mining of Nocardia terpenica IFM 0406

We report a genomics‐guided exploration of the metabolic potential of the brasilicardin producer strain Nocardia terpenica IFM 0406. Bioinformatics analysis of the whole genome sequence revealed the presence of a biosynthetic gene cluster presumably responsible for the generation of formerly unknown...

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Bibliographic Details
Published in:Chembiochem : a European journal of chemical biology 2020-08, Vol.21 (15), p.2205-2213
Main Authors: Chen, Julia, Frediansyah, Andri, Männle, Daniel, Straetener, Jan, Brötz‐Oesterhelt, Heike, Ziemert, Nadine, Kaysser, Leonard, Gross, Harald
Format: Article
Language:English
Subjects:
Acetylcholine receptors (muscarinic)
Bioinformatics
Cytotoxicity
Derivatives
Genomes
Mass spectrometry
Mass spectroscopy
Nocardia
Nucleotide sequence
Siderophores
Toxicity
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