Microsurgery of residual or recurrent complex intracranial aneurysms after coil embolization – a quest for the ultimate therapy

• Published in: Neurosurgical review 2021-04, Vol.44 (2), p.1031-1051
• Main Authors: Pirayesh, Ariyan, Ota, Nakao, Noda, Kosumo, Petrakakis, Ioannis, Kamiyama, Hiroyasu, Tokuda, Sadahisa, Tanikawa, Rokuya
• Format: Article
• Language: English
• Subjects: Medicine; Medicine & Public Health; Neurosurgery; Original Article
• ISSN: 0344-5607; 1437-2320
• DOI: 10.1007/s10143-020-01290-7

The long-term stability of coil embolization (CE) of complex intracranial aneurysms (CIAs) is fraught with high rates of recanalization. Surgery of precoiled CIAs, however, deviates from a common straightforward procedure, demanding sophisticated strategies. To shed light on the scope and limitations of microsurgical re-treatment, we present our experiences with precoiled CIAs. We retrospectively analysed a consecutive series of 12 patients with precoiled CIAs treated microsurgically over a 5-year period, and provide a critical juxtaposition with the literature. Five aneurysms were located in the posterior circulation, 8 were large-giant sized, 5 were calcified/thrombosed. One presented as a dissecting-fusiform aneurysm, 9 ranked among wide neck aneurysms. Eight lesions were excluded by neck clipping (5 necessitating coil extraction); 1 requiring adjunct CE. The dissecting-fusiform aneurysm was resected with reconstruction of the parent artery using a radial artery graft. Three lesions were treated with flow alteration (parent artery occlusion under bypass protection). Mean interval coiling-surgery was 4.6 years (range 0.5–12 years). Overall, 10 aneurysms were successfully excluded; 2 lesions treated with flow alteration displayed partial thrombosis, progressing over time. Outcome was good in 8 and poor in 4 patients (2 experiencing delayed neurological morbidity), and mean follow-up was 24.3 months. No mortality was encountered. Microsurgery as a last resort for precoiled CIAs can provide—in a majority of cases—a definitive therapy with good outcome. Since repeat coiling increases the complexity of later surgical treatment, we recommend for this subgroup of aneurysms a critical evaluation of CE as an option for re-treatment.