Predictors of decline in vitamin D status in middle-aged and elderly individuals: a 5-year follow-up study

Little is known about predictors of decline in vitamin D status (vitamin D decline) over time. We aimed to determine demographic and lifestyle variables associated with vitamin D decline by sufficiently controlling for seasonal effects of vitamin D uptake in a middle-aged to elderly population. Usin...

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Bibliographic Details
Published in:British journal of nutrition 2020-10, Vol.124 (7), p.729-735
Main Authors: Nakamura, Kazutoshi, Kitamura, Kaori, Watanabe, Yumi, Saito, Toshiko, Takahashi, Akemi, Kobayashi, Ryosaku, Oshiki, Rieko, Kabasawa, Keiko, Takachi, Ribeka, Tsugane, Shoichiro, Iki, Masayuki, Sasaki, Ayako, Watanabe, Kei
Format: Article
Language:English
Subjects:
25-Hydroxyvitamin D
Adult
Aged
Aging - blood
Blood
Body size
Calciferol
Chronic illnesses
Cohort analysis
Correlation analysis
Creatinine
Demographic variables
Demographics
Dietary Surveys and Nutritional Epidemiology
Female
Follow-Up Studies
Green tea
Humans
Life Style
Lifestyles
Local government
Longitudinal Studies
Male
Men
Middle age
Middle Aged
Nutritional Status
Older people
Plasma
Population studies
Questionnaires
Regression analysis
Risk Factors
Sex
Sex Factors
Variables
Vitamin D
Vitamin D - analogs & derivatives
Vitamin D - blood
Vitamin D Deficiency - etiology
Vitamin deficiency
Women
Womens health
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Summary:Little is known about predictors of decline in vitamin D status (vitamin D decline) over time. We aimed to determine demographic and lifestyle variables associated with vitamin D decline by sufficiently controlling for seasonal effects of vitamin D uptake in a middle-aged to elderly population. Using a longitudinal study design within the larger framework of the Murakami Cohort Study, we examined 1044 individuals aged between 40 and 74 years, who provided blood samples at baseline and at 5-year follow-up, the latter of which were taken on a date near the baseline examination (±14 d). Blood 25-hydroxyvitamin D (25(OH)D) concentrations were determined with the Liaison® 25OH Vitamin D Total Assay. A self-administered questionnaire collected demographic, body size and lifestyle information. Vitamin D decline was defined as the lowest tertile of 5-year changes in blood 25(OH)D (Δ25(OH)D) concentration (
ISSN:0007-1145
1475-2662
DOI:10.1017/S0007114520001580