Reply to Randal W. Eveland regarding comparative evaluation of the microbicidal activity of low-temperature sterilization technologies to steam sterilization

Because protein (organic matter) remains on cleaned surgical instruments,2 we must investigate at what point the presence of protein overwhelms the ability of the sterilizer to inactivate contaminating microorganisms. [...]regarding environmental hydrogen peroxide levels, for both sterilizers there...

Full description

Saved in:
Bibliographic Details
Published in:Infection control and hospital epidemiology 2020-08, Vol.41 (8), p.1000-1001
Main Authors: Rutala, William A, Gergen, Maria F, Sickbert-Bennett, Emily E, Weber, David J
Format: Article
Language:English
Subjects:
Cold Temperature
Health facilities
Heat
Humans
Hydrogen peroxide
Infections
Low temperature
Medical instruments
Microorganisms
Nursing
Organic matter
Plasma
Proteins
Salt
Steam
Sterilization
Surgical apparatus & instruments
Technology
Temperature
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Because protein (organic matter) remains on cleaned surgical instruments,2 we must investigate at what point the presence of protein overwhelms the ability of the sterilizer to inactivate contaminating microorganisms. [...]regarding environmental hydrogen peroxide levels, for both sterilizers there were no notable emissions from the sterilizers during the cycle. [...]the higher concentration of hydrogen peroxide in the HPGP sterilizer is a potential safety factor, which resulted in the significantly higher margin of safety for HPGP vs VHP (ie, failure rate of HPGP of 1.9% vs 76.3% for VHP).
ISSN:0899-823X
1559-6834
DOI:10.1017/ice.2020.239