Subacromial bursal preservation can enhance rotator cuff tendon regeneration: a comparative rat supraspinatus tendon defect model study

• Published in: Journal of shoulder and elbow surgery 2021-02, Vol.30 (2), p.401-407
• Main Authors: Sun, Yucheng, Kwak, Jae-Man, Kholinne, Erica, Koh, Kyoung-Hwan, Tan, Jun, Jeon, In-Ho
• Format: Article
• Language: English
• Subjects: bone tendon interface; extensive bursectomy; rotator cuff healing; Rotator cuff tear; subacromial bursa; tendon regeneration
• ISSN: 1058-2746; 1532-6500
• DOI: 10.1016/j.jse.2020.05.025

The role of subacromial bursa in rotator cuff surgery is unknown. This study aimed to assess the subacromial bursa's role in the healing of supraspinatus tendon injury in a rat model. Twenty-three male Sprague-Dawley rats (9 weeks old; weight, approximately 296 g) were used in this study. Three rats used as biomechanical study controls were killed at 12 weeks of age. A supraspinatus tendon defect was made bilaterally in 20 rats, whereas an additional subacromial bursa sectioning was performed on the left side. Six rats were killed for biomechanical testing and 4 were killed for histologic observation at 3 and 9 weeks, respectively. The regenerated tendon in the bursal preservation group showed significantly superior biomechanical properties in maximum load to failure at 3 and 9 weeks and stiffness at 9 weeks after surgery compared with the bursal removal group. The modified Bonar scale scores showed better regenerated supraspinatus tendons in the bursal preservation group. The present study found that the subacromial bursa plays an important role in rotator cuff regeneration in this rat supraspinatus injury model. Extensive bursectomy of the subacromial bursa may not be recommended in rotator cuff repair surgery, though future in vivo human studies are needed to confirm these observations.