Differences in in-hospital mortality after STEMI versus NSTEMI by sex. Eleven-year trend in the Spanish National Health Service

• Published in: Revista española de cardiología (English ed.) 2021-06, Vol.74 (6), p.510-517
• Main Authors: Rodríguez-Padial, Luis, Fernández-Pérez, Cristina, Bernal, José L., Anguita, Manuel, Sambola, Antonia, Fernández-Ortiz, Antonio, Elola, Francisco J.
• Format: Article
• Language: English
• Subjects: Acute myocardial infarction; Infarto agudo de miocardio; Infarto de miocardio con elevación del ST; Infarto de miocardio sin elevación del ST; Logistic model; Modelo logístico; Mujeres; Non–ST-elevation myocardial infarction; ST-elevation myocardial infarction; Women
• ISSN: 1885-5857; 1885-5857
• DOI: 10.1016/j.rec.2020.04.017

Conflicting results have been reported on the possible existence of sex differences in mortality after myocardial infarction (MI). There is also a scarcity of data on the impact of sex on outcomes after ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI). The aim of this study was to analyze sex difference trends in sex-related differences in mortality for STEMI and NSTEMI. A retrospective analysis of 445 145 episodes of MI (2005-2015) was carried out using information from the Spanish National Health System. The incidence rates were expressed as events per 10 000 person-years. The denominators (age-specific groups) were obtained from the nationwide census. We calculated crude and adjusted (multilevel logistic regression) mortality. Poisson regression analysis was used to study temporal trends for in-hospital mortality. A total of 69.8% episodes occurred in men. The mean age in men was 66.1±13.3 years, which was significantly younger than in women, 74.9±12.1 (P