Editorial Commentary to Article “The Magnitude of Blood Pressure Reduction Predicts Poor In-hospital Outcome in Acute Intracerebral Hemorrhage” by Divani et al

In this issue of the Neurocritical Care, the authors submit an innovative analysis showing that early aggressive reduction in systolic blood pressure is associated with increased mortality and worse in-hospital outcome after intracerebral hemorrhage (ICH) [1]. Furthermore, the majority of subjects i...

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Bibliographic Details
Published in:Neurocritical care 2020-10, Vol.33 (2), p.362-363
Main Author: Petersen, Nils H.
Format: Article
Language:English
Subjects:
Antihypertensives
Blood Pressure
Cerebral Hemorrhage
Conflicts of interest
Critical Care Medicine
Hematoma
Hemorrhage
Humans
Hypotension
Intensive
Internal Medicine
Invited Editorial Commentary
Medicine
Medicine & Public Health
Neurology
Patients
Pharmacists
Statistical analysis
Stroke
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Summary:In this issue of the Neurocritical Care, the authors submit an innovative analysis showing that early aggressive reduction in systolic blood pressure is associated with increased mortality and worse in-hospital outcome after intracerebral hemorrhage (ICH) [1]. Furthermore, the majority of subjects in the Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH-II) and the Implementation of Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT-2) had small- to moderate-sized hematomas in subcortical locations, leaving those with large and more severe hemorrhages an understudied population. [...]characterizing patients that are likely to benefit remains crucial, and the interaction between timing, intensity, and duration of different BP interventions and outcome requires further definition. Information on blood pressure management or the use of antihypertensive medication is not available, and treatment practices likely varied across centers and during the extended timeframe of data collection.
ISSN:1541-6933
1556-0961
DOI:10.1007/s12028-020-01025-y