Regional oxygen saturation and acute kidney injury in premature infants

Background Decreased renal blood flow plays a vital role in the etiology of acute kidney injury (AKI). In this study, we aim to investigate the role of renal regional oxygen saturation (rSO2) reductions in predicting AKI in the first 24 h of life. Methods One hundred premature babies with a gestatio...

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Bibliographic Details
Published in:Pediatrics international 2021-03, Vol.63 (3), p.290-294
Main Authors: Dorum, Bayram Ali, Ozkan, Hilal, Cetinkaya, Merih, Koksal, Nilgun
Format: Article
Language:English
Subjects:
acute kidney injury
Birth weight
Blood flow
Etiology
Gestational age
Infants
Infrared spectroscopy
Kidneys
near‐infrared spectroscopy
Neonates
newborn
Oxygen
Oxygen saturation
Pediatrics
premature
Premature babies
Premature birth
Statistical analysis
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Summary:Background Decreased renal blood flow plays a vital role in the etiology of acute kidney injury (AKI). In this study, we aim to investigate the role of renal regional oxygen saturation (rSO2) reductions in predicting AKI in the first 24 h of life. Methods One hundred premature babies with a gestational age of ≤32 weeks were included. Renal and cerebral rSO2s were monitored for 24 h by near‐infrared spectroscopy. Infants were followed up for the first 7 days for the diagnosis of AKI. Results Infants' median gestational age was 29 (23–32) weeks, and their birthweight was 1,192 ± 355 g. It was found that the renal rSO2 values were lower in the first 24 h of life in patients who developed AKI, and this decrease was statistically significant in the first 6 h of life. Conclusions The low renal rSO2 values in the early hours of life in premature babies may have a role in predicting AKI.
ISSN:1328-8067
1442-200X
DOI:10.1111/ped.14377