Electromagnetic (EM) catheter path tracking in ultrasound-guided brachytherapy of the breast

• Published in: International journal for computer assisted radiology and surgery 2020-10, Vol.15 (10), p.1645-1652
• Main Authors: Janssen, Natasja N. Y., Brastianos, Harry, Akingbade, Aquila, Olding, Tim, Vaughan, Thomas, Ungi, Tamas, Lasso, Andras, Joshi, Chandra, Korzeniowski, Martin, Falkson, Conrad, Fichtinger, Gabor
• Format: Article
• Language: English
• Subjects: Accuracy; Brachytherapy - methods; Breast - diagnostic imaging; Breast Neoplasms - diagnostic imaging; Breast Neoplasms - radiotherapy; Catheters; Computer Imaging; Computer Science; Electromagnetic Phenomena; Evaluation; Female; Ground truth; Health Informatics; Humans; Imaging; Implantation; Medicine; Medicine & Public Health; Metric space; Navigation systems; Original Article; Path tracking; Pattern Recognition and Graphics; Phantoms, Imaging; Radiation therapy; Radiology; Radiotherapy Dosage; Software; Surgery; Tumors; Ultrasonic imaging; Ultrasonography, Interventional - methods; Ultrasound; Vision
• ISSN: 1861-6410; 1861-6429
• DOI: 10.1007/s11548-020-02233-9

Purpose To evaluate a novel navigation system for breast brachytherapy, based on ultrasound (US)-guided catheter needle implantations followed by electromagnetic (EM) tracking of catheter paths. Methods Breast phantoms were produced, containing US–visible tumors. Ultrasound was used to localize the tumor pose and volume within the phantom, followed by planning an optimal catheter pattern through the tumor using navigation software. An electromagnetic (EM)-tracked catheter needle was used to insert the catheters in the desired pattern. The inserted catheters were visualized on a post-implant CT, serving as ground truth. Electromagnetic (EM) tracking and reconstruction of the inserted catheter paths were performed by pulling a flexible EM guidewire through each catheter, performed in two clinical brachytherapy suites. The accuracy of EM catheter tracking was evaluated by calculating the Hausdorff distance between the EM-tracked and CT-based catheter paths. The accuracy and clinical feasibility of EM catheter tracking were also evaluated in three breast cancer patients, performed in a separate experiment room. Results A total of 71 catheter needles were implanted into 12 phantoms using US guidance and EM navigation, in an average ± SD time of 8.1 ± 2.9 min. The accuracy of EM catheter tracking was dependent on the brachytherapy suite: 2.0 ± 1.2 mm in suite 1 and 0.6 ± 0.2 mm in suite 2. EM catheter tracking was successfully performed in three breast brachytherapy patients. Catheter tracking typically took less than 5 min and had an average accuracy of 1.7 ± 0.3 mm. Conclusion Our preliminary results show a potential role for US guidance and EM needle navigation for implantation of catheters for breast brachytherapy. EM catheter tracking can accurately assess the implant geometry in breast brachytherapy patients. This methodology has the potential to evaluate catheter positions directly after the implantation and during the several fractions of the treatment.