Structure‐function of platelet glycoprotein Ib‐IX

The glycoprotein (GP)Ib‐IX receptor complex plays a critical role in platelet physiology and pathology. Its interaction with von Willebrand factor (VWF) on the subendothelial matrix instigates platelet arrest at the site of vascular injury and is vital to primary hemostasis. Its reception to other l...

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Bibliographic Details
Published in:Journal of thrombosis and haemostasis 2020-12, Vol.18 (12), p.3131-3141
Main Authors: Quach, M. Edward, Li, Renhao
Format: Article
Language:English
Subjects:
Blood Platelets
glycoprotein Ib
Glycoproteins
Hemostasis
Humans
Ligands
mechanoreceptor
platelet
Platelet Glycoprotein GPIb-IX Complex
Platelets
Structure-function relationships
thrombocytopenia
thrombosis
Von Willebrand factor
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