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Chronic rhinosinusitis disease burden is associated with asthma-related emergency department usage

Purpose Chronic rhinosinusitis (CRS) disease burden is associated with pulmonary status in asthmatic CRS patients. Asthma-related emergency department (ED) usage is a predictor of asthma-related mortality. We sought to determine whether measures of CRS disease burden are associated with asthma-relat...

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Bibliographic Details
Published in:European archives of oto-rhino-laryngology 2021, Vol.278 (1), p.93-99
Main Authors: Gleadhill, Claire, Speth, Marlene M., Gengler, Isabelle, Phillips, Katie M., Hoehle, Lloyd P., Caradonna, David S., Gray, Stacey T., Sedaghat, Ahmad R.
Format: Article
Language:English
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Summary:Purpose Chronic rhinosinusitis (CRS) disease burden is associated with pulmonary status in asthmatic CRS patients. Asthma-related emergency department (ED) usage is a predictor of asthma-related mortality. We sought to determine whether measures of CRS disease burden are associated with asthma-related ED usage. Methods We prospectively recruited 263 asthmatic CRS patients for this cross-sectional study. CRS burden was measured using the 22-item Sinonasal Outcome Test (SNOT-22), and patient-reported CRS-related antibiotic usage and CRS-related oral corticosteroids usage over the preceding year. Asthma-related ED visits over the prior year were also assessed. Results Of all participants, 18.6% had at least 1 asthma-related ED visit (mean 0.3 ED visits for the whole cohort). Asthma-related ED usage was associated with SNOT-22 score [adjusted rate ratio (RR) = 1.02, 95% CI 1.01–1.03, p  = 0.040] and CRS-related oral corticosteroids usage in the past year (RR = 1.52, 95% CI 1.26–1.83, p  
ISSN:0937-4477
1434-4726
DOI:10.1007/s00405-020-06259-2