Coexistence of brown tumors due to secondary hyperparathyroidism and prostate cancer in a patient

We present the case of a 65-year-old man with brown tumors due to secondary hyperparathyroidism. Magnetic resonance imaging of the pelvis showed multiple lesions with expansive bone appearance. Additionally, prostate cancer was diagnosed during this time. For this reason, differential diagnosis was...

Full description

Saved in:
Bibliographic Details
Published in:Osteoporosis international 2021-01, Vol.32 (1), p.205-208
Main Authors: Abdala, Ruben, Gonzalez Pernas, Mariana S.
Format: Article
Language:English
Subjects:
Aged
Biopsy
Bone cancer
Bone imaging
Bone lesions
Bone tumors
Case Report
Case reports
Coexistence
Diagnosis, Differential
Differential diagnosis
Endocrinology
Humans
Hyperparathyroidism
Hyperparathyroidism, Secondary - complications
Magnetic resonance imaging
Male
Medicine
Medicine & Public Health
Metastases
Orthopedics
Osteitis Deformans - complications
Osteitis Fibrosa Cystica - complications
Osteitis Fibrosa Cystica - diagnosis
Osteoclasts
Paraneoplastic syndrome
Parathyroid
Parathyroid hormone
Parathyroid hormone-related protein
Pelvis
Prostate cancer
Prostatic Neoplasms - complications
Rheumatology
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We present the case of a 65-year-old man with brown tumors due to secondary hyperparathyroidism. Magnetic resonance imaging of the pelvis showed multiple lesions with expansive bone appearance. Additionally, prostate cancer was diagnosed during this time. For this reason, differential diagnosis was performed through biopsy of the right iliac bone lesion. Brown tumors are caused by osteoclastic activity and fibroblast proliferation; the differential diagnosis of these bone lesions includes giant tumors, metastases, Paget’s disease, and paraneoplastic syndrome with high levels of parathyroid hormone-related peptide (PTHrP). This case report describes the coexistence of two pathologies that could explain these images. In this report, we present a case of a 65-year-old man with brown tumors due to secondary hyperparathyroidism and prostate cancer. In this setting, histologic confirmation is recommended.
ISSN:0937-941X
1433-2965
DOI:10.1007/s00198-020-05558-y