Medical expert system for low back pain management: design issues and conflict resolution with Bayesian network

• Published in: Medical & biological engineering & computing 2020-11, Vol.58 (11), p.2737-2756
• Main Authors: Santra, Debarpita, Mandal, Jyotsna Kumar, Basu, Swapan Kumar, Goswami, Subrata
• Format: Article
• Language: English
• Subjects: Biomedical and Life Sciences; Biomedical Engineering and Bioengineering; Biomedicine; Computer Applications; Human Physiology; Imaging; Original Article; Radiology
• ISSN: 0140-0118; 1741-0444
• DOI: 10.1007/s11517-020-02222-9

The paper focuses on the development of a reliable medical expert system for diagnosis of low back pain (LBP) by proposing an efficient frame-based knowledge representation scheme and a suitable resolution logic with conflicts in outcomes being resolved using Bayesian network. Considering that LBP is classified into many diseases based on different pain generators, the proposed methodology infers non-conflicting LBP diseases sorted according to their chances of occurrence. A satisfactory clinical efficacy (average relative error − 0.09, recall 74.44%, precision 76.67%, accuracy 71.11%, and F 1-score 73.88%) of the proposed methodology has been found after validating the design with empirically selected thirty LBP patient cases. Constraining that an inferred disease having chance of occurrence, prior to pathological investigations, below 0.75 (as set by four pain specialists) is not accepted clinically; the design can correctly identify, on average, 74.44% of actual diagnosis; and 76.67% of inferred diagnosis is included in actual diagnosis. With the predicted chance of occurrence being lower than 0.75 by a fraction of 0.09 on average, the proposed design performs well for 73.88% cases detecting 71.11% inferred outcomes as accurate. The design offers homogeneity to the actual outcomes, with the chi-squared static being calculated as 11.08 having 12 as degree of freedom. Graphical abstract