Construction and structure-activity mechanism of polysaccharide nano-selenium carrier

[Display omitted] •The water solubility of polysaccharides was improved by sulfation modification.•The water-soluble sulfated polysaccharides were used as stabilizer.•Size-controlled and stable nano-selenium particles were prepared via one-step way.•Size-dependent bioactivities of the prepared nano-...

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Bibliographic Details
Published in:Carbohydrate polymers 2020-05, Vol.236, p.116052, Article 116052
Main Authors: Hu, Shuqian, Hu, Weicheng, Li, Yanru, Li, Shujing, Tian, Huafeng, Lu, Ang, Wang, Jianguo
Format: Article
Language:English
Subjects:
Anti-inflammatory activity
gene expression
lipopolysaccharides
macrophages
nanoparticles
nitric oxide
Polysaccharides
selenium
Selenium nanoparticles
Structure-activity relationship
sulfates
water solubility
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