Effects of rhythmic auditory stimulation on upper-limb movement speed in patients with schizophrenia spectrum disorders

Movement slowness, linked to dysfunctional basal ganglia and cerebellum, is prevalent but lacks effective therapy in patients with schizophrenia spectrum disorders. This study was to examine immediate effects of rhythmic auditory stimulation (RAS) on upper-limb movement speed in patients. Thirty pat...

Full description

Saved in:
Bibliographic Details
Published in:European archives of psychiatry and clinical neuroscience 2021-12, Vol.271 (8), p.1445-1453
Main Authors: Wang, Shu-Mei, Lin, Chung-Ying, Tse, Tracy Ho-Yan, Chu, Hin-Lun, Liu, Cheong-Ho, Ng, Tsz-Ho, Tse, Chun-Kwok, Wong, Wai-Man, Chan, Sunny Ho-Wan
Format: Article
Language:English
Subjects:
Acoustic Stimulation
Basal ganglia
Cerebellum
Heredity
Humans
Medicine
Medicine & Public Health
Mental disorders
Movement - physiology
Neurosciences
Original Paper
Psychiatry
Rhythms
Schizophrenia
Schizophrenia - physiopathology
Schizophrenia - therapy
Treatment Outcome
Upper Extremity - physiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Movement slowness, linked to dysfunctional basal ganglia and cerebellum, is prevalent but lacks effective therapy in patients with schizophrenia spectrum disorders. This study was to examine immediate effects of rhythmic auditory stimulation (RAS) on upper-limb movement speed in patients. Thirty patients and 30 psychiatrically healthy people executed the right-hand task and the both-hand task of the Purdue Pegboard Test when listening to RAS with two tempi: normal (equal to the fastest movement tempo for each participant without RAS) and fast (120% of the normal tempo). The testing order of the RAS tempi for each participant was randomized. Patients had lower scores of right-hand and both-hand tasks than did psychiatrically healthy people. Scores of right-hand and both-hand tasks were higher in the fast-RAS condition than the normal-RAS condition in participants. This is the first study to explore the possibility of applying RAS to movement therapy for patients with schizophrenia spectrum disorders. The results demonstrated that faster RAS was effective in inducing faster upper-limb movements in patients and psychiatrically healthy people, suggesting that manipulating RAS may be a feasible therapeutic strategy utilized to regulate movement speed. The RAS may involve alternative neural pathways to modulate movement speed and thus to compensate for impaired function of basal ganglia and cerebellum in patients.
ISSN:0940-1334
1433-8491
DOI:10.1007/s00406-020-01193-0